HitPredict

Interactor 1: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Interactor 2: EGLN3 (Q9H6Z9)
Prolyl hydroxylase EGLN3 (EC 1.14.11.-) (Egl nine homolog 3) (EC 1.14.11.29) (HPH-1) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3)
Gene: EGLN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	25416956, 26972000
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 619 Hs			1 239
+	Hs
		978895 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00
+	Rn
		887089 Q7TQN4_RAT (2-576): 2.12e-167: 490: 38.48		EGLN1_RAT (2-225): 6.51e-146: 412: 64.29
+	Hs
		1021744 NFAC3_HUMAN (1-610): 1.34e-128: 406: 15.35		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00
+	Hs
		318020 NFAC1_HUMAN (1-486): 1.55e-76: 264: 15.32		EGLN3_HUMAN (1-239): 5.66e-162: 449: 100.00