HitPredict

Interactor 1: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22665060
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 261
+	Hs
		983372 DYN1_HUMAN (1-864): 0: 1087: 100.00		MYO1E_HUMAN (36-261): 8.28e-25: 105: 15.04
+	Hs
		983416 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN3_HUMAN (7-261): 3.62e-25: 104: 17.07
+	Hs
		983404 DYN1_HUMAN (1-864): 0: 1087: 100.00		SH3G1_HUMAN (48-261): 6.99e-24: 100: 18.81
+	Hs
		983392 DYN1_HUMAN (1-864): 0: 1087: 100.00		NOSTN_HUMAN (39-261): 9.75e-23: 98.8: 15.86
+	Hs
		983405 DYN1_HUMAN (1-864): 0: 1087: 100.00		SH3G2_HUMAN (47-261): 5.88e-23: 98: 18.14
+	Mm
		760451 DYN1_MOUSE (1-845): 0: 1081: 99.65		PACN1_MOUSE (7-261): 1.63e-24: 103: 19.48
+	Hs
		983406 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN1_HUMAN (6-261): 2.88e-22: 96.9: 19.09
+	Rn
		193636 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G1_RAT (48-261): 1.99e-23: 99.2: 16.97
+	Mm
		760453 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G1_MOUSE (48-261): 1.19e-23: 99: 16.97
+	Rn
		192351 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G2_RAT (47-261): 8.45e-23: 97.2: 16.74
+	Mm
		760454 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G2_MOUSE (47-261): 9.83e-23: 97.2: 17.21
+	Rn
		599414 DYN1_RAT (1-864): 0: 1081: 98.03		PACN1_RAT (6-261): 1.47e-21: 94.9: 17.26
+	Mm
		760455 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G3_MOUSE (47-261): 6.15e-22: 94.9: 16.06
+	Rn
		192355 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G3_RAT (47-261): 1.28e-21: 94.2: 16.06
+	Hs
		282319 DYN2_HUMAN (1-860): 0: 1021: 78.91		NEBL_HUMAN (36-261): 8.63e-29: 116: 31.67
+	Hs
		207784 DYN2_HUMAN (1-860): 0: 1021: 78.91		PPIP1_HUMAN (3-261): 4.41e-28: 112: 15.47
+	Mm
		760487 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN2_MOUSE (15-261): 2.6e-26: 108: 17.94
+	Mm
		760485 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN3_MOUSE (7-261): 2.45e-25: 105: 17.77
+	Mm
		760475 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN1_MOUSE (7-261): 1.63e-24: 103: 19.48
+	Mm
		760473 DYN2_MOUSE (1-860): 0: 1022: 79.13		SRC8_MOUSE (59-260): 8.14e-23: 99.2: 21.68