HitPredict

Interactor 1: SWR1 (Q05471)
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)
Gene: SWR1

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.975

Property	Details
Experiments	16299513, 15045029, 26116819, 30309918, 19088068, 14645854, 16239141, 17289584, 19106085, 37968396, 21179020
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1514 Sc			1 134
+	Sc
		392201 SWR1_YEAST (1-1514): 0: 1057: 100.00		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392572 SWR1_YEAST (1-1514): 0: 1057: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	At
		1186949 PIE1_ARATH (188-1495): 0: 714: 31.24		H2AV2_ARATH (1-129): 4.55e-54: 167: 61.48
+	At
		1186947 PIE1_ARATH (188-1495): 0: 714: 31.24		H2AV3_ARATH (4-130): 3.12e-52: 163: 60.90
+	At
		188586 PIE1_ARATH (188-1495): 0: 714: 31.24		H2AV1_ARATH (5-130): 3.75e-52: 162: 60.45
+	Sp
		142453 SWR1_SCHPO (219-1511): 0: 701: 40.39		H2AZ_SCHPO (18-130): 1.98e-47: 151: 73.45
+	Hs
		1087132 INO80_HUMAN (210-1444): 0: 644: 23.37		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		391964 INO80_HUMAN (210-1444): 0: 644: 23.37		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		229433 SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69		H2A2B_HUMAN (7-129): 3.24e-52: 162: 56.45
+	Hs
		1018640 CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89		H2A1H_HUMAN (7-133): 5.62e-52: 162: 55.47
+	Hs
		229286 SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		470170 CHD8_HUMAN (1034-1508): 5.26e-80: 295: 23.70		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		470128 EP400_HUMAN (1098-1509): 2.23e-76: 284: 27.52		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		469951 SMCA1_HUMAN (1060-1503): 5.31e-78: 283: 26.51		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		229279 SMCA5_HUMAN (1033-1509): 3.54e-85: 304: 24.69		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Mm
		470232 SMCA4_MOUSE (1036-1484): 5.49e-74: 275: 20.85		H2AZ_MOUSE (10-134): 6.73e-41: 134: 67.72
+	Hs
		391675 CHD3_HUMAN (1017-1463): 2.27e-80: 296: 24.89		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391915 CHD8_HUMAN (1034-1508): 5.26e-80: 295: 23.70		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391728 CHD9_HUMAN (1108-1510): 5.26e-78: 288: 26.18		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Hs
		391846 EP400_HUMAN (1098-1509): 2.23e-76: 284: 27.52		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83