HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: AIF1L (Q9BQI0)
Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2)
Gene: AIF1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0051017 - actin filament bundle assembly
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 150
+	Hs
		984656 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		EFHD1_HUMAN (1-109): 2.98e-35: 124: 31.19
+	Ce
		104561 G5EBY3_CAEEL (3-792): 1.41e-34: 144: 11.81		CALM_CAEEL (41-149): 1.24e-29: 106: 23.21
+	Hs
		1268065 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		EFHD2_HUMAN (1-109): 3.03e-29: 108: 29.36
+	Hs
		484173 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		CALM3_HUMAN (41-149): 7.38e-30: 107: 23.21
+	Hs
		725216 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		EFHD2_HUMAN (1-109): 3.03e-29: 108: 29.36
+	Dm
		1303398 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		EFHD2_DROME (24-120): 1.4e-30: 111: 29.90
+	Hs
		724955 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		EFHD2_HUMAN (1-109): 3.03e-29: 108: 29.36
+	Hs
		648467 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		CALL3_HUMAN (34-115): 1.68e-22: 88.6: 17.44
+	Hs
		484206 MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38		CALM3_HUMAN (41-149): 7.38e-30: 107: 23.21
+	Dm
		54870 A1ZA72_DROME (138-632): 5.06e-09: 62.2: 17.72		CALM_DROME (41-149): 1.51e-29: 106: 23.21
+	Hs
		551861 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		CALL5_HUMAN (49-112): 2.95e-09: 53.9: 28.13