HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: NEB1 (Q9ULJ8)
Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A)
Gene: PPP1R9A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 1098
+	Hs
		984650 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Mm
		936586 ROCK2_MOUSE (1-688): 4.34e-24: 111: 11.48		DLG4_MOUSE (376-1098): 3.11e-50: 192: 13.00
+	Rn
		192527 MYH10_RAT (55-785): 3.7e-26: 117: 10.67		NEB2_RAT (1-826): 2.53e-45: 178: 43.42
+	Mm
		936587 ROCK2_MOUSE (1-688): 4.34e-24: 111: 11.48		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		1164008 MYH9_MOUSE (2-638): 2.4e-23: 108: 10.87		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		1143165 MYH10_MOUSE (1-631): 1.18e-22: 106: 9.40		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		93558 DESP_MOUSE (13-637): 1.8e-22: 105: 13.96		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		724975 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		NEB2_HUMAN (1-826): 1.2e-42: 170: 43.65
+	Mm
		1164088 PLEC_MOUSE (5-781): 5.88e-19: 94.9: 9.56		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Mm
		93873 E9QPE7_MOUSE (2-490): 8.16e-18: 91: 13.59		NEB2_MOUSE (1-826): 5.97e-43: 171: 43.42
+	Hs
		876402 GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Dm
		113458 Q9VIF7_DROME (256-532): 1.18e-20: 99.8: 17.33		M9NFI9_DROME (837-1057): 2.21e-28: 126: 23.89
+	Rn
		361106 MYH6_RAT (1-792): 1.31e-29: 129: 10.29		MYH6_RAT (574-1090): 2.87e-15: 83.3: 11.28
+	Hs
		522657 MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45		MYH7_HUMAN (574-1091): 5.37e-12: 72.9: 11.59
+	Hs
		528435 MYH4_HUMAN (1-788): 6.02e-31: 133: 10.45		MYH8_HUMAN (612-1091): 8.14e-12: 72: 12.05
+	Dm
		1303380 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		PATJ_DROME (213-593): 2.18e-17: 89.8: 15.66
+	Hs
		876385 GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43		AFAD_HUMAN (419-593): 1.96e-23: 110: 30.11
+	Hs
		528432 MYH13_HUMAN (1-698): 3.34e-21: 101: 12.00		MYH8_HUMAN (612-1091): 8.14e-12: 72: 12.05
+	Hs
		1047698 KI16B_HUMAN (113-599): 8.25e-21: 100: 15.99		IL16_HUMAN (152-648): 4.59e-09: 62.9: 16.31