Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11
Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.33 | 1.00 | 0.575 |
The method score is based on:
Property | Details |
---|---|
Experiments | unassigned1853 |
Identification Methods | anti tag coimmunoprecipitation |
Interaction Type | association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | LRR_8~SH2 |
Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030159 - signaling receptor complex adaptor activity GO:0032760 - positive regulation of tumor necrosis factor production |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024