HitPredict

Interactor 1: PTN11 (Q06124)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1D) (PTP-1D) (Protein-tyrosine phosphatase 2C) (PTP-2C) (SH-PTP2) (SHP-2) (Shp2) (SH-PTP3)
Gene: PTPN11

Interactor 2: FCRL3 (Q96P31)
Fc receptor-like protein 3 (FcR-like protein 3) (FcRL3) (Fc receptor homolog 3) (FcRH3) (IFGP family protein 3) (hIFGP3) (Immune receptor translocation-associated protein 3) (MAIA) (SH2 domain-containing phosphatase anchor protein 2) (CD antigen CD307c)
Gene: FCRL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12051764
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1990782 - protein tyrosine kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 593 Hs			1 734
+	Hs
		665941 PTN6_HUMAN (6-593): 0: 531: 55.27		FCRL3_HUMAN (11-734): 1.85e-144: 442: 100.00
+	Hs
		985950 PTN11_HUMAN (1-593): 0: 581: 100.00		PTK7_HUMAN (290-732): 2.85e-50: 192: 15.27
+	Hs
		590601 PTN6_HUMAN (6-593): 0: 531: 55.27		CD22_HUMAN (50-655): 2.89e-55: 205: 14.31
+	Hs
		665883 PTN6_HUMAN (6-593): 0: 531: 55.27		PTK7_HUMAN (290-732): 2.85e-50: 192: 15.27
+	Mm
		682308 PTN11_MOUSE (1-593): 0: 580: 99.49		CEAM1_MOUSE (59-382): 6.9e-33: 135: 19.76
+	Mm
		719301 PTN11_MOUSE (1-593): 0: 580: 99.49		PECA1_MOUSE (16-408): 3.07e-28: 123: 16.87
+	Hs
		557450 PTN11_HUMAN (1-593): 0: 581: 100.00		PECA1_HUMAN (16-371): 2.73e-26: 117: 17.69
+	Mm
		665992 PTN6_MOUSE (6-583): 0: 530: 55.94		FCRL5_MOUSE (158-647): 1.01e-43: 168: 16.10
+	Hs
		685206 PTN11_HUMAN (1-593): 0: 581: 100.00		FCG2B_HUMAN (1-202): 2.42e-19: 91.3: 30.62
+	Hs
		519378 PTN11_HUMAN (1-593): 0: 581: 100.00		FCG2A_HUMAN (16-186): 3.57e-16: 82: 30.34
+	Hs
		986005 PTN11_HUMAN (1-593): 0: 581: 100.00		FCGRB_HUMAN (3-168): 2.89e-13: 72.8: 29.71
+	Hs
		557436 PTN6_HUMAN (6-593): 0: 531: 55.27		PECA1_HUMAN (16-371): 2.73e-26: 117: 17.69
+	Mm
		665976 PTN6_MOUSE (6-583): 0: 530: 55.94		CD22_MOUSE (315-734): 7.77e-25: 112: 11.91
+	Hs
		665804 PTN6_HUMAN (6-593): 0: 531: 55.27		FCG2B_HUMAN (1-202): 2.42e-19: 91.3: 30.62
+	Hs
		441175 PTPRC_HUMAN (33-579): 2.25e-85: 291: 18.29		CD22_HUMAN (50-655): 2.89e-55: 205: 14.31
+	Hs
		616914 PTPRB_HUMAN (147-555): 2.35e-115: 379: 27.91		CNTN1_HUMAN (433-733): 4.26e-20: 97.8: 12.46
+	Hs
		616927 PTPRB_HUMAN (147-555): 2.35e-115: 379: 27.91		NRCAM_HUMAN (22-639): 4.82e-15: 81.6: 10.71
+	Hs
		616990 PTPRD_HUMAN (39-522): 2.1e-115: 379: 26.76		MILR1_HUMAN (397-564): 2.77e-10: 64.7: 33.14
+	Gg
		47583 A0A8V0YWD3_CHICK (33-522): 1.95e-110: 353: 24.25		CNTN1_CHICK (491-733): 2.57e-15: 82.4: 12.08
+	Hs
		617163 PTPRZ_HUMAN (33-537): 1.15e-65: 235: 16.73		CNTN1_HUMAN (433-733): 4.26e-20: 97.8: 12.46