HitPredict

Interactor 1: SFH1 (Q06168)
Chromatin structure-remodeling complex subunit SFH1 (RSC complex subunit SFH1) (SNF5 homolog 1)
Gene: SFH1

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	16554755, 16429126, 37968396, 21701592, 14729968, 12183366, 12805231, 27768892, 17949749, 32496195, 32188943, 22177115
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006337 - nucleosome disassembly GO:0006338 - chromatin remodeling GO:0006368 - transcription elongation by RNA polymerase II GO:0007059 - chromosome segregation GO:0016586 - RSC-type complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 426 Sc			1 889
+	Sc
		728762 SFH1_YEAST (1-426): 0: 644: 100.00		BDF1_YEAST (26-219): 5.23e-19: 94.4: 12.63
+	Sc
		860447 SFH1_YEAST (1-426): 0: 644: 100.00		RSC1_YEAST (4-149): 1.8e-12: 73.6: 18.24
+	Sc
		696258 SFH1_YEAST (1-426): 0: 644: 100.00		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		969421 SFH1_YEAST (1-426): 0: 644: 100.00		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84
+	Hs
		1017131 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Mm
		1150297 SNF5_MOUSE (174-407): 4.27e-104: 315: 27.87		SMCA2_MOUSE (9-178): 4.14e-31: 134: 24.42
+	Mm
		1111974 SNF5_MOUSE (174-407): 4.27e-104: 315: 27.87		SMCA4_MOUSE (9-122): 2.28e-30: 131: 30.17
+	Rn
		1117300 Q4KLI0_RAT (174-407): 2.7e-104: 315: 27.87		SMCA4_RAT (9-122): 2.2e-30: 131: 30.17
+	Hs
		631412 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		846949 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		846761 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		SMCA2_HUMAN (9-150): 9.42e-28: 123: 24.07
+	Hs
		244353 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1017144 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		BRDT_HUMAN (1-263): 1.78e-25: 115: 13.11
+	Hs
		1017241 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		1017159 SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87		PB1_HUMAN (234-742): 1.78e-19: 96.7: 14.64
+	Dm
		631293 Q24090_DROME (187-407): 4.45e-100: 304: 27.48		BRM_DROME (265-375): 1.03e-10: 67.9: 26.13
+	Sc
		577127 SNF5_YEAST (177-382): 6.44e-64: 222: 25.34		SNF2_YEAST (8-168): 6.81e-25: 114: 23.93
+	Sc
		577146 SNF5_YEAST (177-382): 6.44e-64: 222: 25.34		SPT7_YEAST (158-404): 1.37e-18: 93.5: 11.86