HitPredict

Interactor 1: SMD2 (Q06217)
Small nuclear ribonucleoprotein Sm D2 (Sm-D2) (snRNP core protein D2)
Gene: SMD2

Interactor 2: LSM6 (Q06406)
U6 snRNA-associated Sm-like protein LSm6
Gene: LSM6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	10900456, 16429126
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... GO:0071001 - U4/U6 snRNP
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 110 Sc			1 86
+	Hs
		912218 SMD2_HUMAN (5-109): 2.21e-47: 149: 52.68		LSM6_HUMAN (10-85): 1.6e-34: 114: 46.05
+	Hs
		911794 SMD2_HUMAN (5-109): 2.21e-47: 149: 52.68		RUXF_HUMAN (12-82): 9.86e-32: 107: 35.21
+	Ce
		712467 SMD2_CAEEL (1-109): 6.77e-50: 155: 48.28		RUXF_CAEEL (12-82): 8.57e-29: 100: 29.58
+	Dm
		1367661 SMD2_DROME (5-109): 3.64e-47: 148: 51.79		Q9W2P5_DROME (13-85): 1.72e-31: 106: 42.47
+	Dm
		1097027 SMD2_DROME (5-109): 3.64e-47: 148: 51.79		RUXF_DROME (12-82): 2.82e-29: 101: 35.21
+	Sc
		873667 SMD2_YEAST (1-110): 1.11e-48: 152: 100.00		RUXF_YEAST (12-83): 5.95e-24: 87.8: 28.77