Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Interactor 2: IKZF3 (Q9UKT9)
Zinc finger protein Aiolos (Ikaros family zinc finger protein 3)
Gene: IKZF3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 0.60 | 0.707 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 27107012, 32296183, unassigned1304 |
| Identification Methods | two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, barcode fusion genetics two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
