HitPredict

Interactor 1: UTP4 (Q06679)
U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4)
Gene: UTP4

Interactor 2: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31662437, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 776 Sc			1 733
+	Sc
		635667 PWP2_YEAST (244-720): 2.31e-37: 152: 6.64		RRP6_YEAST (1-733): 0: 736: 100.00
+	Sc
		630899 NLE1_YEAST (516-647): 4.72e-13: 74.3: 12.03		RRP6_YEAST (1-733): 0: 736: 100.00
+	Hs
		966394 TBL3_HUMAN (341-716): 1.33e-23: 108: 9.09		EXOSX_HUMAN (10-725): 0: 624: 28.35
+	Hs
		966502 WDR3_HUMAN (275-595): 1.21e-20: 99.6: 17.13		EXOSX_HUMAN (10-725): 0: 624: 28.35
+	Hs
		966451 UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48		EXOSX_HUMAN (10-725): 0: 624: 28.35
+	Hs
		903139 WDR5_HUMAN (522-737): 1.2e-20: 95.7: 8.41		EXOSX_HUMAN (10-725): 0: 624: 28.35
+	Hs
		1050615 UTP4_HUMAN (410-699): 2.84e-20: 98: 8.48		WRN_HUMAN (223-654): 1.79e-95: 325: 12.96
+	Hs
		1050616 SNR40_HUMAN (182-501): 2.76e-12: 71.1: 15.27		WRN_HUMAN (223-654): 1.79e-95: 325: 12.96