HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: NBEL2 (Q6ZNJ1)
Neurobeachin-like protein 2
Gene: NBEAL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29187380
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 632 Hs			1 2754
+	Hs
		844117 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		NBEL2_HUMAN (1-2754): 0: 2873: 100.00
+	Mm
		729591 FMR1_MOUSE (1-632): 0: 1063: 93.99		NBEA_MOUSE (411-1311): 0: 715: 16.63
+	Mm
		1207094 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		NBEA_MOUSE (411-1311): 0: 715: 16.63
+	Hs
		903160 FMR1_HUMAN (1-632): 0: 1106: 100.00		WDR5_HUMAN (2586-2753): 1.82e-40: 156: 8.72
+	Hs
		989045 FMR1_HUMAN (1-632): 0: 1106: 100.00		FBXW7_HUMAN (2358-2525): 6.44e-20: 99.6: 13.64
+	Mm
		729521 FMR1_MOUSE (1-632): 0: 1063: 93.99		WDFY3_MOUSE (2625-2752): 1.91e-10: 69.1: 12.14
+	Hs
		843596 FXR1_HUMAN (1-334): 0: 604: 73.95		WDR5_HUMAN (2586-2753): 1.82e-40: 156: 8.72
+	Mm
		1167197 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		WDFY3_MOUSE (2625-2752): 1.91e-10: 69.1: 12.14
+	Hs
		843829 FXR1_HUMAN (1-334): 0: 604: 73.95		FBXW7_HUMAN (2358-2525): 6.44e-20: 99.6: 13.64
+	Hs
		843604 FXR1_HUMAN (1-334): 0: 604: 73.95		RACK1_HUMAN (2590-2751): 4.46e-20: 95.7: 14.02
+	Hs
		843998 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		WDR5_HUMAN (2586-2753): 1.82e-40: 156: 8.72
+	Hs
		844003 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		RACK1_HUMAN (2590-2751): 4.46e-20: 95.7: 14.02