HitPredict

Interactor 1: SRF1 (Q06BH3)
Protein STRUBBELIG-RECEPTOR FAMILY 1 (Leucine-rich repeat receptor kinase-like protein SRF1)
Gene: SRF1

Interactor 2: NIK1 (Q9LFS4)
Protein NSP-INTERACTING KINASE 1 (AtNIK1) (EC 2.7.11.1) (LRR receptor-like serine/threonine-protein kinase NIK1)
Gene: NIK1

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29320478, 30806640
Identification Methods	pull down, solid phase assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LRR_1~LRR_1, LRR_1~LRRNT_2, LRR_1~LRR_8, LRR_8~LRRNT_2, LRR_8~PK_Tyr_Ser-Thr, LRRNT_2~LRRNT_2, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms	GO:0004672 - protein kinase activity GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 775 At			1 638
+	At
		1163633 SRF8_ARATH (9-767): 0: 660: 42.09		NIK1_ARATH (1-638): 0: 719: 100.00
+	At
		1013308 SRF8_ARATH (9-767): 0: 660: 42.09		Y2239_ARATH (5-638): 0: 651: 60.47
+	At
		1163620 SRF8_ARATH (9-767): 0: 660: 42.09		BAK1_ARATH (13-638): 0: 647: 48.65
+	At
		1163616 SRF8_ARATH (9-767): 0: 660: 42.09		Y4052_ARATH (5-638): 0: 640: 58.17
+	At
		1163618 SRF8_ARATH (9-767): 0: 660: 42.09		SERK1_ARATH (13-638): 0: 639: 51.02
+	At
		1163648 SRF8_ARATH (9-767): 0: 660: 42.09		SERK4_ARATH (37-638): 0: 613: 49.51
+	At
		989589 SRF1_ARATH (1-775): 0: 622: 100.00		BAK1_ARATH (13-638): 0: 647: 48.65
+	At
		85008 SRF8_ARATH (9-767): 0: 660: 42.09		Y5457_ARATH (9-638): 0: 604: 51.09
+	At
		989588 SRF1_ARATH (1-775): 0: 622: 100.00		Y4052_ARATH (5-638): 0: 640: 58.17
+	At
		84819 SRF1_ARATH (1-775): 0: 622: 100.00		Y5129_ARATH (7-638): 0: 612: 45.16
+	At
		1163617 SRF8_ARATH (9-767): 0: 660: 42.09		Y5371_ARATH (19-638): 0: 551: 41.56
+	At
		1163621 SRF8_ARATH (9-767): 0: 660: 42.09		Y5838_ARATH (9-604): 4.12e-180: 526: 28.75
+	At
		1163641 SRF8_ARATH (9-767): 0: 660: 42.09		BIR2_ARATH (13-602): 2e-167: 493: 28.62
+	At
		84518 SRF1_ARATH (1-775): 0: 622: 100.00		Y4245_ARATH (2-614): 8.87e-176: 524: 26.66
+	At
		84266 SRF1_ARATH (1-775): 0: 622: 100.00		C0LGM1_ARATH (7-637): 5.77e-174: 520: 26.30
+	At
		1163643 SRF8_ARATH (9-767): 0: 660: 42.09		Y5830_ARATH (12-607): 1.79e-157: 469: 27.39
+	At
		83935 SRF8_ARATH (9-767): 0: 660: 42.09		Y1699_ARATH (24-611): 1.14e-156: 465: 31.16
+	At
		83932 SRF1_ARATH (1-775): 0: 622: 100.00		Y1699_ARATH (24-611): 1.14e-156: 465: 31.16
+	At
		1163644 SRF8_ARATH (9-767): 0: 660: 42.09		Y5639_ARATH (24-219): 2.19e-25: 114: 20.09
+	At
		1163634 SRF8_ARATH (9-767): 0: 660: 42.09		BRL3_ARATH (83-194): 2.98e-09: 62.4: 28.05