HitPredict

Interactor 1: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	25533188, 37071664, 37059091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 1834
+	Hs
		964359 SUMO2_HUMAN (1-97): 1.78e-38: 125: 45.36		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		939209 SUMO3_HUMAN (1-97): 1.66e-37: 123: 47.42		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		1314312 NF2IP_HUMAN (10-90): 2.2e-25: 99.4: 26.83		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		853979 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		853965 SUMO2_HUMAN (1-97): 1.78e-38: 125: 45.36		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		964340 SUMO2_HUMAN (1-97): 1.78e-38: 125: 45.36		SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50
+	Hs
		964282 SUMO2_HUMAN (1-97): 1.78e-38: 125: 45.36		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		1253854 NF2IP_HUMAN (10-90): 2.2e-25: 99.4: 26.83		SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50