HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: STK3 (Q13188)
Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2) (MST-2) (STE20-like kinase MST2) (Serine/threonine-protein kinase Krs-1) [Cleaved into: Serine/threonine-protein kinase 3 36kDa subunit (MST2/N); Serine/threonine-protein kinase 3 20kDa subunit (MST2/C)]
Gene: STK3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37739411
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 491
+	Hs
		991790 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		STK24_HUMAN (16-325): 1.92e-124: 371: 50.32
+	Hs
		138823 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		STK25_HUMAN (9-426): 1.56e-123: 369: 40.28
+	Hs
		991631 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		Q8NBY1_HUMAN (22-402): 4.77e-124: 369: 44.68
+	Hs
		991742 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		STK26_HUMAN (22-392): 1.22e-122: 366: 44.27
+	Hs
		1390735 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		STK26_HUMAN (22-392): 1.22e-122: 366: 44.27
+	Hs
		991509 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		PAK1_HUMAN (6-302): 9.24e-119: 361: 41.81
+	Hs
		1096477 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		PAK1_HUMAN (6-302): 9.24e-119: 361: 41.81
+	Hs
		991623 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		MINK1_HUMAN (5-316): 3.36e-70: 244: 43.43