HitPredict

Interactor 1: DYL1 (P63168)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN) (mPIN)
Gene: Dynll1

Interactor 2: NDE1 (Q9CZA6)
Nuclear distribution protein nudE homolog 1 (NudE) (mNudE)
Gene: NDE1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	21911489, 11163258
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005874 - microtubule GO:0019904 - protein domain specific binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Mm			1 344
+	Hs
		991702 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		NDEL1_HUMAN (3-342): 1.13e-78: 246: 54.49
+	Hs
		1390712 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		NDEL1_HUMAN (3-342): 1.13e-78: 246: 54.49
+	Hs
		991737 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		NDE1_HUMAN (1-311): 7.22e-78: 243: 91.00
+	Hs
		1390732 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		NDE1_HUMAN (1-311): 7.22e-78: 243: 91.00
+	Mm
		991807 DYL1_MOUSE (1-89): 1.97e-46: 145: 100.00		NDEL1_MOUSE (3-342): 1.03e-75: 238: 54.78
+	Hs
		991656 DYL1_HUMAN (1-89): 1.97e-46: 145: 100.00		CTTB2_HUMAN (36-343): 1.06e-58: 206: 15.09
+	Hs
		1362026 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		CTTB2_HUMAN (36-343): 1.06e-58: 206: 15.09
+	Hs
		1277767 DYL2_HUMAN (1-89): 1.69e-45: 142: 93.26		MYH14_HUMAN (2-203): 1.25e-29: 121: 19.31