HitPredict

Interactor 1: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.49	0.60	0.545

Property	Details
Experiments	22745667, unassigned1973
Identification Methods	unspecified method, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 1292
+	Mm
		1141333 KHDR1_MOUSE (1-443): 0: 514: 94.36		NCK1_MOUSE (708-1005): 1.97e-49: 182: 17.63
+	Hs
		537634 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		NCF1_HUMAN (701-1015): 3.76e-50: 185: 17.18
+	Hs
		557667 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		NCK1_HUMAN (708-1005): 1.37e-49: 182: 18.27
+	Hs
		209037 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		NCK2_HUMAN (767-1019): 1.85e-42: 162: 16.23
+	Hs
		991805 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		DNMBP_HUMAN (796-1253): 2.23e-17: 90.7: 14.23
+	Hs
		991778 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		ITSN1_HUMAN (273-858): 7.03e-15: 82.5: 10.91
+	Hs
		991902 KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00		ITSN2_HUMAN (1079-1290): 3.39e-12: 73.7: 14.49
+	Hs
		209060 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		NCK2_HUMAN (767-1019): 1.85e-42: 162: 16.23
+	Hs
		1052207 SF01_HUMAN (82-301): 6.63e-54: 192: 21.33		SRC8_HUMAN (991-1288): 1.92e-23: 108: 13.38