HitPredict

Interactor 1: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	32088314, 24999239
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005743 - mitochondrial inner membrane GO:0005783 - endoplasmic reticulum and 4 others more... GO:0005829 - cytosol GO:0043524 - negative regulation of neuron apoptotic process GO:0051881 - regulation of mitochondrial membrane potential GO:2001243 - negative regulation of intrinsic apoptotic signaling pathway
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	233
Hs

1	581

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024