Protein: TRM3
tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34) (tRNA [Gm18] ribose methylase) (tRNA methyltransferase 3)

Gene: TRM3
Organism: Saccharomyces cerevisiae S288C
Interactions: 25
UniProt ID: Q07527

Gene Ontology (top 5):
GO:0002128 - tRNA nucleoside ribose methylation
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0016423 - tRNA (guanine) methyltransferase activity
GO:0030488 - tRNA methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1059558

TRM3
tRNA

1

9

High-throughput

0.618

High

795684

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

2

0

High-throughput

0.595

High

450652

FAS1
Fatty acid synthase subunit beta

2

0

High-throughput

0.585

High

510857

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.536

High

642482

MCK1
Protein kinase MCK1

1

1

High-throughput

0.536

High

818492

LSM5
LSM complex subunit LSM5

1

1

High-throughput

0.508

High

1042987

THADA
tRNA

1

0

High-throughput

0.458

High

1059559

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

546473

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

580151

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

597284

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

676399

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

742516

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

752798

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

918475

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

597760

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

871454

HLJ1
Protein HLJ1

1

2

High-throughput

0.407

High

796853

SIF2
SIR4-interacting protein SIF2

1

0

High-throughput

0.279

Low

680104

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

708330

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

805845

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

808557

TEM1
Protein TEM1

1

0

High-throughput

0.249

Low

825026

TAO3
Cell morphogenesis protein PAG1

1

0

High-throughput

0.249

Low

918287

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025