Interactor 1: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1
Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.971 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32203420, 10716926, 20936779, 37219487, 35914814, 18539136, 15824104, unassigned2213 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, unspecified method, anti tag coimmunoprecipitation, two hybrid pooling approach, two hybrid fragment pooling approach, experimental interaction detection, coimmunoprecipitation, imaging technique |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~RhoGEF, PH~SH3_1, PH~SH3_9, RasGEF_N~RhoGEF, PH_13~RhoGEF, RhoGEF~RhoGEF, RhoGEF~SH3_1, RhoGEF~SH3_9 |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
