HitPredict

Interactor 1: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: FOXF1 (Q12946)
Forkhead box protein F1 (Forkhead-related activator 1) (FREAC-1) (Forkhead-related protein FKHL5) (Forkhead-related transcription factor 1)
Gene: FOXF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 4544 Hs			1 379
+	Hs
		992658 LRP1_HUMAN (24-4544): 0: 3520: 100.00		FOXF2_HUMAN (44-379): 7.6e-81: 256: 51.11
+	Hs
		992701 LRP1_HUMAN (24-4544): 0: 3520: 100.00		FOXB1_HUMAN (37-304): 2.32e-53: 181: 28.21
+	Hs
		980392 NOTC2_HUMAN (2441-2811): 3.71e-13: 79.1: 10.70		FX4L6_HUMAN (10-250): 6.21e-50: 174: 33.20
+	Hs
		1110364 SORL_HUMAN (4091-4375): 6.29e-11: 71.4: 12.95		FX4L6_HUMAN (10-250): 6.21e-50: 174: 33.20
+	Hs
		351072 LDLR_HUMAN (4062-4338): 4.81e-10: 68.3: 11.95		FX4L6_HUMAN (10-250): 6.21e-50: 174: 33.20
+	Hs
		1110381 LRP1B_HUMAN (2-280): 8.74e-09: 64.5: 16.93		FX4L6_HUMAN (10-250): 6.21e-50: 174: 33.20
+	Hs
		1169828 SORL_HUMAN (4091-4375): 6.29e-11: 71.4: 12.95		FOXI2_HUMAN (45-137): 7.93e-26: 107: 59.14