HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: DHX36 (Q9H2U1)
ATP-dependent DNA/RNA helicase DHX36 (EC 3.6.4.12) (EC 3.6.4.13) (DEAD/H box polypeptide 36) (DEAH-box protein 36) (G4-resolvase-1) (G4R1) (MLE-like protein 1) (RNA helicase associated with AU-rich element protein)
Gene: DHX36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1008
+	Hs
		1028815 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		1029088 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		952120 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		DHX36_HUMAN (1-1008): 0: 1048: 100.00
+	Hs
		994145 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX9_HUMAN (57-1005): 0: 841: 33.02
+	Hs
		1028910 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Hs
		993717 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Hs
		992770 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Hs
		1028697 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Hs
		1028960 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Bt
		898864 PABP1_BOVIN (8-203): 7.41e-38: 141: 16.67		DHX9_BOVIN (57-1005): 0: 839: 33.02
+	Hs
		993741 SRSF4_HUMAN (17-243): 1.36e-49: 171: 37.66		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Hs
		992812 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		DHX57_HUMAN (68-990): 0: 805: 38.48
+	Hs
		224784 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX16_HUMAN (41-926): 0: 772: 24.02
+	Hs
		1028710 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1028972 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1055380 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		DHX8_HUMAN (4-951): 0: 835: 21.18
+	Hs
		992826 SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		952009 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1084313 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		DHX30_HUMAN (187-963): 0: 764: 35.38
+	Hs
		1029095 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		YTDC2_HUMAN (199-411): 1.08e-49: 194: 47.20