HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 1164
+	Hs
		993485 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Hs
		522544 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH1_HUMAN (393-967): 5.76e-21: 102: 11.23
+	Hs
		980905 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH2_HUMAN (393-980): 6.89e-21: 101: 11.32
+	Hs
		980924 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH4_HUMAN (393-969): 2.58e-19: 96.8: 11.22
+	Hs
		522607 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH7_HUMAN (391-922): 3.39e-17: 89.9: 8.59
+	Hs
		528407 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH8_HUMAN (822-1163): 6.53e-11: 69.1: 10.73
+	Hs
		502910 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		MYH3_HUMAN (400-850): 1.77e-10: 67.9: 10.00