Protein: FOXL2
Forkhead box protein L2

Gene: FOXL2
Organism: Homo sapiens
Interactions: 67
UniProt ID: P58012

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

945694

FOXL2
Forkhead box protein L2

1

19

High-throughput

0.575

High

349019

LATS1
Serine/threonine-protein kinase LATS1

1

4

Small-scale

0.573

High

945696

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.561

High

123071

DX39A
ATP-dependent RNA helicase DDX39A

1

10

High-throughput

0.536

High

139508

PESC
Pescadillo homolog

1

1

High-throughput

0.536

High

173688

BTAF1
TATA-binding protein-associated factor 172

1

20

High-throughput

0.536

High

182947

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.536

High

215869

AN32C
Putative uncharacterized protein ANP32CP

1

3

High-throughput

0.536

High

238876

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

3

High-throughput

0.536

High

333976

SMC2
Structural maintenance of chromosomes protein 2

1

14

High-throughput

0.536

High

794421

RBMX
RNA-binding motif protein, X chromosome

1

8

High-throughput

0.536

High

834408

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

13

High-throughput

0.536

High

929765

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.536

High

945697

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.536

High

945700

UBE4A
Ubiquitin conjugation factor E4 A

1

4

High-throughput

0.536

High

945701

TTF1
Transcription termination factor 1

1

2

High-throughput

0.536

High

945702

SIX1
Homeobox protein SIX1

1

20

High-throughput

0.536

High

945704

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

12

High-throughput

0.536

High

945705

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

5

High-throughput

0.536

High

945707

LARP7
La-related protein 7

1

6

High-throughput

0.536

High

945708

SYDM
Aspartate--tRNA ligase, mitochondrial

1

5

High-throughput

0.536

High

945710

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.536

High

945716

G45IP
Large ribosomal subunit protein mL64

1

3

High-throughput

0.536

High

945717

DNJC9
DnaJ homolog subfamily C member 9

1

4

High-throughput

0.536

High

945722

FUBP3
Far upstream element-binding protein 3

1

13

High-throughput

0.536

High

945723

ZFR
Zinc finger RNA-binding protein

1

8

High-throughput

0.536

High

945724

POP1
Ribonucleases P/MRP protein subunit POP1

1

1

High-throughput

0.536

High

945726

DCNL5
DCN1-like protein 5

1

1

High-throughput

0.536

High

945727

MOV10
Helicase MOV-10

1

1

High-throughput

0.536

High

945730

TAP26
Thyroid transcription factor 1-associated protein 26

1

1

High-throughput

0.536

High

945731

PUF60
Poly(U)-binding-splicing factor PUF60

1

4

High-throughput

0.536

High

945732

TTF2
Transcription termination factor 2

1

20

High-throughput

0.536

High

945733

DDX52
Probable ATP-dependent RNA helicase DDX52

1

6

High-throughput

0.536

High

945734

TR150
Thyroid hormone receptor-associated protein 3

1

5

High-throughput

0.536

High

249448

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

5

High-throughput

0.489

High

477772

RM03
Large ribosomal subunit protein uL3m

1

4

High-throughput

0.489

High

566949

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

4

High-throughput

0.489

High

687773

SYVC
Valine--tRNA ligase

1

14

High-throughput

0.489

High

914072

HXK2
Hexokinase-2

1

6

High-throughput

0.489

High

945703

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

5

High-throughput

0.489

High

945709

LARP1
La-related protein 1

1

5

High-throughput

0.489

High

945714

TRM2A
tRNA

1

2

High-throughput

0.489

High

945718

NU205
Nuclear pore complex protein Nup205

1

4

High-throughput

0.489

High

945719

RM24
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.489

High

945720

NSUN4
5-cytosine rRNA methyltransferase NSUN4

1

3

High-throughput

0.489

High

945725

CMS1
Protein CMSS1

1

3

High-throughput

0.489

High

945729

NSMA3
Sphingomyelin phosphodiesterase 4

1

6

High-throughput

0.489

High

117165

J9JIF5
CXXC-type zinc finger protein 4

1

3

Small-scale

0.479

High

135792

RTCA
RNA 3'-terminal phosphate cyclase

1

1

High-throughput

0.479

High

285624

BAF
Barrier-to-autointegration factor

1

2

Small-scale

0.479

High

315347

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

557993

XRCC6
X-ray repair cross-complementing protein 6

1

1

Small-scale

0.479

High

559747

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

20

Small-scale

0.479

High

659195

SP100
Nuclear autoantigen Sp-100

1

20

Small-scale

0.479

High

945695

H4
Histone H4

1

4

High-throughput

0.479

High

945698

SMAD3
Mothers against decapentaplegic homolog 3

1

7

Small-scale

0.479

High

945699

CREM
cAMP-responsive element modulator

1

7

Small-scale

0.479

High

945706

GLYR1
Cytokine-like nuclear factor N-PAC

1

6

High-throughput

0.479

High

945711

CXXC5
CXXC-type zinc finger protein 5

1

3

Small-scale

0.479

High

945713

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.479

High

945721

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

3

Small-scale

0.479

High

945735

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

3

Small-scale

0.479

High

428100

RLA1
Large ribosomal subunit protein P1

1

2

Small-scale

0.437

High

945712

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.279

Low

945715

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

945728

RT18A
Large ribosomal subunit protein mL66

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025