HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 2229
+	Hs
		516546 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		992995 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1029163 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		965152 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		ANK2_HUMAN (315-2229): 1.67e-52: 207: 10.29
+	Hs
		993872 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1028876 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		993011 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		516749 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		1029050 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		992772 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		1029046 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		516766 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		1028547 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		516609 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Dm
		644444 SRR55_DROME (3-175): 1.29e-46: 168: 63.64		Q9VLS7_DROME (949-2220): 1.76e-09: 65.6: 9.45
+	Hs
		516406 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		1031405 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		820908 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		820889 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24