HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36373674
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 1101
+	Hs
		992838 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1028988 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1028576 SRSF9_HUMAN (3-216): 2.36e-52: 178: 36.53		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		516583 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1221731 PABP3_HUMAN (3-189): 1.09e-28: 121: 19.19		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		1031385 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Hs
		963547 TIAR_HUMAN (96-188): 2.66e-10: 63.8: 16.67		SMC5_HUMAN (1-1101): 5.88e-124: 409: 100.00
+	Sc
		376836 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		SMC3_YEAST (51-1055): 7.78e-71: 260: 13.66