HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: DDX31 (Q9H8H2)
ATP-dependent DNA helicase DDX31 (EC 3.6.4.12) (DEAD box protein 31) (Helicain) (Probable ATP-dependent RNA helicase DDX31) (EC 3.6.4.13)
Gene: DDX31

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 851
+	Hs
		992938 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX31_HUMAN (1-851): 0: 616: 100.00
+	Hs
		1029098 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX31_HUMAN (1-851): 0: 616: 100.00
+	Hs
		1028823 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX31_HUMAN (1-851): 0: 616: 100.00
+	Hs
		1308773 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		DDX31_HUMAN (1-851): 0: 616: 100.00
+	Hs
		1029127 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX18_HUMAN (154-753): 2.72e-163: 492: 31.53
+	Hs
		1028843 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX18_HUMAN (154-753): 2.72e-163: 492: 31.53
+	Hs
		1029007 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX55_HUMAN (225-762): 5.96e-161: 483: 29.80
+	Sc
		742058 NOP4_YEAST (1-492): 1.19e-52: 190: 11.82		HAS1_YEAST (195-775): 4.81e-147: 444: 31.39
+	Hs
		133858 PABP1_HUMAN (1-189): 4.04e-31: 128: 19.50		DDX3X_HUMAN (73-667): 6.93e-135: 418: 21.28
+	Mm
		1208005 RBM4_MOUSE (1-218): 3.79e-19: 90.8: 23.85		DDX18_MOUSE (101-804): 7.24e-145: 444: 27.40
+	Mm
		936480 TIAR_MOUSE (3-105): 3.23e-13: 73.1: 19.05		DDX5_MOUSE (110-817): 9.78e-141: 432: 20.96
+	Mm
		857351 TIA1_MOUSE (98-188): 7.57e-10: 62.7: 17.02		Q8BTS0_MOUSE (110-817): 7.93e-140: 429: 20.96
+	Hs
		134018 PABP4_HUMAN (100-185): 3.19e-11: 67.7: 19.78		DDX3X_HUMAN (73-667): 6.93e-135: 418: 21.28
+	Mm
		857323 TIA1_MOUSE (98-188): 7.57e-10: 62.7: 17.02		DDX17_MOUSE (137-662): 3.38e-130: 405: 23.76
+	Hs
		992749 SRSF1_HUMAN (3-166): 2.36e-57: 192: 41.42		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Hs
		1027880 SRSF6_HUMAN (1-180): 4.52e-52: 181: 78.50		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Hs
		993699 SRSF4_HUMAN (1-468): 4.56e-48: 174: 100.00		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Hs
		1027879 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Hs
		1027924 RBM4B_HUMAN (3-104): 4.68e-11: 66.1: 23.08		DDX10_HUMAN (254-754): 2.78e-64: 233: 34.20
+	Sc
		376628 PABP_YEAST (72-188): 2.61e-10: 64.6: 14.75		DBP4_YEAST (254-648): 2.72e-58: 215: 36.36