HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 431
+	Hs
		980945 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		980631 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		980820 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		980959 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		316865 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		993504 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		ZN383_HUMAN (46-218): 1.26e-09: 62: 10.92
+	Ce
		137683 UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47		SPTF2_CAEEL (270-372): 1.27e-34: 128: 54.37
+	Ce
		137695 UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47		KLF1_CAEEL (268-376): 5.08e-26: 111: 50.46