HitPredict

Interactor 1: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26725010, 29845934, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1270 Hs			1 582
+	Hs
		403200 DHX9_HUMAN (1-1241): 0: 1275: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Bt
		898864 DHX9_BOVIN (1-1169): 0: 1225: 94.78		PABP1_BOVIN (1-405): 1.94e-40: 157: 10.29
+	Hs
		994218 DHX9_HUMAN (1-1241): 0: 1275: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		994182 DHX9_HUMAN (1-1241): 0: 1275: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Mm
		250448 DHX9_MOUSE (1-1169): 0: 1208: 93.00		ELAV1_MOUSE (92-211): 6.43e-13: 71.9: 22.50
+	Hs
		1116540 DHX36_HUMAN (258-1158): 0: 820: 32.70		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116361 DHX29_HUMAN (249-1143): 0: 768: 30.91		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116324 DHX57_HUMAN (99-1142): 0: 765: 28.74		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		195457 DHX15_HUMAN (361-1076): 0: 742: 25.00		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403338 DHX36_HUMAN (258-1158): 0: 820: 32.70		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		1268165 DHX36_HUMAN (258-1158): 0: 820: 32.70		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Sc
		376861 PRP43_YEAST (320-1103): 0: 820: 26.18		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		1288627 DHX36_HUMAN (258-1158): 0: 820: 32.70		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1055487 DHX8_HUMAN (51-1122): 0: 810: 20.54		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		1158090 DHX57_HUMAN (99-1142): 0: 765: 28.74		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		1190220 DHX29_HUMAN (249-1143): 0: 768: 30.91		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1158103 DHX57_HUMAN (99-1142): 0: 765: 28.74		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Dm
		1179711 DHX15_DROME (375-1076): 0: 785: 25.66		LARP_DROME (38-120): 1.58e-13: 76.1: 35.23
+	Hs
		1116346 DHX30_HUMAN (381-1093): 3.3e-123: 412: 33.96		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		403266 DHX30_HUMAN (381-1093): 3.3e-123: 412: 33.96		LA_HUMAN (24-365): 5.96e-44: 163: 18.83