HitPredict

Interactor 1: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Interactor 2: NOP53 (Q12080)
Ribosome biogenesis protein NOP53 (Nucleolar protein 53)
Gene: NOP53

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37968396, 37811893
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005730 - nucleolus GO:0008097 - 5S rRNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 291 Sc			1 455
+	Hs
		1255226 BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91		NOP53_HUMAN (32-455): 3.52e-82: 263: 21.69
+	Hs
		1332925 RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57		NOP53_HUMAN (32-455): 3.52e-82: 263: 21.69
+	Hs
		1291775 IMP4_HUMAN (13-255): 9.01e-73: 227: 15.79		NOP53_HUMAN (32-455): 3.52e-82: 263: 21.69
+	Sc
		733972 RPF2_YEAST (6-282): 1.45e-61: 199: 16.84		NOP53_YEAST (1-455): 8.5e-86: 272: 100.00
+	Sc
		755349 RPF1_YEAST (4-252): 5.84e-52: 173: 14.40		NOP53_YEAST (1-455): 8.5e-86: 272: 100.00
+	Hs
		1343149 SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87		NOP53_HUMAN (32-455): 3.52e-82: 263: 21.69
+	Sc
		754934 SSF1_YEAST (10-197): 9.05e-34: 129: 15.64		NOP53_YEAST (1-455): 8.5e-86: 272: 100.00
+	Sc
		1014978 SSF2_YEAST (10-197): 8.32e-33: 127: 15.17		NOP53_YEAST (1-455): 8.5e-86: 272: 100.00