HitPredict

Interactor 1: RBX1 (Q08273)
RING-box protein HRT1 (RING-box protein 1) (E3 ubiquitin-protein ligase complex SCF subunit HRT1) (High level expression reduces Ty3 transposition protein 1) (Regulator of cullins protein 1)
Gene: HRT1

Interactor 2: CDC53 (Q12018)
Cell division control protein 53 (Cullin-A) (E3 ubiquitin ligase complex SCF subunit CDC53)
Gene: CDC53

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 10213692, 11283612, 10385629, 11805837, 20832729, 10213691, 18206966, 19763088, 14747994, 15988528, 18719252, 19942853, 19882662, 23267104, 14690591
Identification Methods coimmunoprecipitation, affinity chromatography technology, anti tag coimmunoprecipitation, enzymatic study, pull down, biochemical, two hybrid, miniaturized immunoprecipitation, two hybrid array, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000409 - regulation of transcription by galactose
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 121
Sc

1 815
+ Hs
+ Mm
+ Dm
+ Hs
+ Mm
+ At
+ Hs
+ Mm
+ Hs
+ Sp
+ Dm
+ At
+ Hs
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+ At
+ Ce
+ Dm
+ Hs
+ Sp
+ Ce

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Last updated: 15 Jul 2024