HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	22057045
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 461
+	Hs
		655337 DDR1_HUMAN (1-913): 0: 911: 100.00		P85A_HUMAN (48-455): 9.1e-92: 295: 79.17
+	Hs
		129284 DDR1_HUMAN (1-913): 0: 911: 100.00		P85B_HUMAN (56-453): 2.19e-87: 283: 74.12
+	Hs
		412153 DDR1_HUMAN (1-913): 0: 911: 100.00		FYN_HUMAN (326-459): 6.82e-20: 94.2: 26.06
+	Hs
		782782 DDR1_HUMAN (1-913): 0: 911: 100.00		CSK_HUMAN (357-456): 1.18e-19: 93: 34.65
+	Hs
		433332 DDR1_HUMAN (1-913): 0: 911: 100.00		YES_HUMAN (317-459): 6.84e-19: 91.2: 23.72
+	Hs
		522939 DDR1_HUMAN (1-913): 0: 911: 100.00		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Hs
		433722 DDR1_HUMAN (1-913): 0: 911: 100.00		LYN_HUMAN (298-458): 6.17e-18: 88.1: 24.85
+	Hs
		994689 DDR1_HUMAN (1-913): 0: 911: 100.00		VAV3_HUMAN (44-159): 6.81e-16: 82.5: 30.17
+	Hs
		855789 DDR1_HUMAN (1-913): 0: 911: 100.00		VAV2_HUMAN (38-159): 4.46e-13: 73.7: 22.95
+	Hs
		523011 DDR2_HUMAN (20-905): 0: 843: 51.46		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Hs
		337329 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		ABL1_HUMAN (3-461): 1.02e-93: 308: 16.12
+	Hs
		129185 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		P85B_HUMAN (56-453): 2.19e-87: 283: 74.12
+	Mm
		403406 SRC_MOUSE (361-912): 1.24e-128: 399: 23.65		SRC_MOUSE (323-459): 7.66e-19: 91.2: 24.14
+	Gg
		337663 SRC_CHICK (371-912): 5.37e-126: 392: 23.35		SRC_CHICK (323-459): 3.26e-19: 92.3: 24.83
+	Rn
		1376717 SRC_RAT (361-912): 4.24e-126: 393: 23.42		SRC_RAT (323-459): 5.91e-19: 91.2: 24.14
+	Rn
		693648 SRC_RAT (361-912): 4.24e-126: 393: 23.42		CSK_RAT (286-457): 6.83e-19: 90.8: 24.86
+	Rn
		989767 SRC_RAT (361-912): 4.24e-126: 393: 23.42		LYN_RAT (298-458): 7.79e-19: 90.8: 24.85
+	Mm
		403451 SRC_MOUSE (361-912): 1.24e-128: 399: 23.65		SHC2_MOUSE (30-162): 1.52e-14: 77.9: 30.83
+	Mm
		403440 SRC_MOUSE (361-912): 1.24e-128: 399: 23.65		SHC3_MOUSE (32-162): 4.26e-13: 72.9: 29.77
+	Hs
		181783 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		SOCS1_HUMAN (46-169): 5.58e-13: 69.8: 23.20