HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: RAB21 (Q9UL25)
Ras-related protein Rab-21
Gene: RAB21

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 225
+	Hs
		894740 DDR2_HUMAN (20-905): 0: 843: 51.46		RAB8A_HUMAN (13-221): 7.3e-97: 282: 37.32
+	Hs
		1088155 DDR2_HUMAN (20-905): 0: 843: 51.46		RAB21_HUMAN (1-225): 8.99e-90: 265: 100.00
+	Hs
		522882 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		523004 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		RB11B_HUMAN (9-224): 1e-84: 252: 32.72
+	Hs
		507934 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RAB8A_HUMAN (13-221): 7.3e-97: 282: 37.32
+	Hs
		507935 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RAB14_HUMAN (10-221): 5.83e-96: 280: 33.95
+	Hs
		609604 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		RAB21_HUMAN (1-225): 8.99e-90: 265: 100.00
+	Hs
		609444 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		RAB2B_HUMAN (15-222): 1.97e-87: 259: 32.56
+	Hs
		508124 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RAB2B_HUMAN (15-222): 1.97e-87: 259: 32.56
+	Hs
		507936 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RAB1A_HUMAN (9-222): 6.14e-87: 257: 32.24
+	Hs
		508023 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RB11B_HUMAN (9-224): 1e-84: 252: 32.72
+	Hs
		433312 YES_HUMAN (563-907): 1.25e-105: 339: 31.59		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		507848 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		433295 YES_HUMAN (563-907): 1.25e-105: 339: 31.59		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82
+	Hs
		433251 YES_HUMAN (563-907): 1.25e-105: 339: 31.59		RAB5A_HUMAN (10-224): 2.26e-49: 162: 41.28
+	Hs
		384608 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Rn
		69428 INSR_RAT (600-908): 1.98e-51: 198: 36.25		B0BMW0_RAT (10-221): 5.83e-96: 280: 33.95
+	Hs
		411350 INSR_HUMAN (600-908): 7.71e-53: 202: 37.42		RB11A_HUMAN (9-224): 6.96e-85: 252: 32.41
+	Hs
		384514 NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82
+	Hs
		411339 INSR_HUMAN (600-908): 7.71e-53: 202: 37.42		RAB5C_HUMAN (1-224): 1.01e-51: 168: 39.82