HitPredict

Interactor 1: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22057045
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 2541
+	Hs
		523226 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		TLN1_HUMAN (1-2541): 0: 1534: 100.00
+	Hs
		719462 DDR1_HUMAN (1-913): 0: 911: 100.00		MERL_HUMAN (80-638): 1.03e-92: 316: 14.79
+	Hs
		547024 DDR1_HUMAN (1-913): 0: 911: 100.00		EZRI_HUMAN (84-666): 2.76e-85: 294: 14.65
+	Hs
		523221 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		E41L3_HUMAN (78-1116): 3.01e-115: 397: 11.42
+	Hs
		299238 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		FARP2_HUMAN (55-1039): 1.12e-121: 415: 12.54
+	Hs
		508287 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		FARP1_HUMAN (52-1026): 1.66e-112: 388: 11.82
+	Hs
		523010 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		PTN21_HUMAN (64-973): 1.47e-87: 316: 12.49
+	Hs
		507884 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		MERL_HUMAN (80-638): 1.03e-92: 316: 14.79
+	Hs
		607900 FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87		MERL_HUMAN (80-638): 1.03e-92: 316: 14.79
+	Hs
		507828 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		EZRI_HUMAN (84-666): 2.76e-85: 294: 14.65
+	Hs
		546928 FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87		EZRI_HUMAN (84-666): 2.76e-85: 294: 14.65
+	Hs
		609192 FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16		RADI_HUMAN (84-666): 2.05e-80: 280: 13.96
+	Hs
		507885 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		RADI_HUMAN (84-666): 2.05e-80: 280: 13.96
+	Hs
		607901 FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87		RADI_HUMAN (84-666): 2.05e-80: 280: 13.96
+	Hs
		507865 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		607883 FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		508011 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		PLEC_HUMAN (730-2529): 2.6e-23: 111: 12.52
+	Hs
		523100 SRC_HUMAN (361-912): 1.28e-125: 391: 23.60		FERM2_HUMAN (268-416): 1.69e-11: 72: 27.82
+	Hs
		601499 FGFR2_HUMAN (583-905): 4.2e-109: 357: 34.05		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63
+	Hs
		508139 FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52		FERM2_HUMAN (268-416): 1.69e-11: 72: 27.82