Interactor 1: DSC1 (Q08554)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
Gene: DSC1

Interactor 2: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 9214392
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin
Common GO terms GO:0001533 - cornified envelope
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0030057 - desmosome
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024