HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: KAT6A (Q92794)
Histone acetyltransferase KAT6A (EC 2.3.1.48) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (MYST-3) (Monocytic leukemia zinc finger protein) (Runt-related transcription factor-binding protein 2) (Zinc finger protein 220)
Gene: KAT6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006334 - nucleosome assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 2004
+	Hs
		309695 SSRP1_HUMAN (1-709): 0: 805: 100.00		KAT7_HUMAN (166-780): 5.67e-142: 457: 33.76
+	Hs
		996636 SSRP1_HUMAN (1-709): 0: 805: 100.00		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		996673 SSRP1_HUMAN (1-709): 0: 805: 100.00		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		996804 SSRP1_HUMAN (1-709): 0: 805: 100.00		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		996788 SSRP1_HUMAN (1-709): 0: 805: 100.00		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Sc
		710451 POB3_YEAST (4-504): 0: 541: 29.66		SAS3_YEAST (486-860): 1.72e-122: 410: 32.69
+	Hs
		881822 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		KAT5_HUMAN (292-779): 3.96e-132: 426: 34.82
+	Hs
		727856 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		CHD3_HUMAN (37-504): 1.12e-72: 273: 14.40
+	Hs
		1059807 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		CHD4_HUMAN (63-504): 3.51e-50: 199: 11.13
+	Hs
		1270673 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		881820 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		DPF1_HUMAN (87-322): 3.58e-58: 208: 31.25
+	Hs
		818826 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		DPF1_HUMAN (87-322): 3.58e-58: 208: 31.25
+	Hs
		881821 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		818827 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		REQU_HUMAN (39-326): 5.71e-54: 196: 27.24
+	Hs
		881818 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Hs
		818824 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		PHF10_HUMAN (183-318): 2.33e-41: 162: 43.36
+	Hs
		152619 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61
+	Hs
		152611 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61
+	Hs
		152690 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		KMT2D_HUMAN (193-311): 2.94e-25: 117: 33.61
+	Hs
		818819 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		KMT2C_HUMAN (229-311): 4.1e-22: 107: 37.35