HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 27173435, 12393879, 24981860, 35271311, 36765085, 16902406, 16682447, 28514442, 30021884, 33961781, 37071682, 19214185, 16713563, 21055985
Identification Methods affinity chromatography technology, pull down, biochemical, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains POB3_N~SPT16, Rtt106~Rtt106, Rtt106~SPT16, SPT16~SSrecog
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0006281 - DNA repair
and 4 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 709
Hs

1 1047
+ Dm
+ Ce
+ Ce
+ At
+ Tt
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024