Protein: KDM6B
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) (Lysine demethylase 6B) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B)

Gene: KDM6B
Organism: Homo sapiens
Interactions: 93
UniProt ID: O15054

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002437 - inflammatory response to antigenic stimulus
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

165861

KDM7A
Lysine-specific demethylase 7A

2

5

Small-scale

0.789

High

165797

KDM6B
Lysine-specific demethylase 6B

1

16

Small-scale

0.618

High

165832

ANM2
Protein arginine N-methyltransferase 2

2

2

Small-scale

0.614

High

165869

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

13

Small-scale

0.584

High

165888

SCC4
MAU2 chromatid cohesion factor homolog

2

0

Small-scale

0.559

High

165844

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

165856

H2B2E
Histone H2B type 2-E

1

14

High-throughput

0.536

High

165809

H12
Histone H1.2

1

3

High-throughput

0.515

High

165839

CSK2B
Casein kinase II subunit beta

1

4

High-throughput

0.508

High

165840

H31
Histone H3.1

1

18

Small-scale

0.501

High

165821

PROF2
Profilin-2

1

3

High-throughput

0.489

High

165805

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

165866

CBP
CREB-binding protein

1

19

Small-scale

0.481

High

165798

KLF4
Krueppel-like factor 4

1

20

Small-scale

0.479

High

165801

DNJA2
DnaJ homolog subfamily A member 2

1

6

Small-scale

0.479

High

165802

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

3

Small-scale

0.479

High

165804

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

165808

VAV
Proto-oncogene vav

1

7

Small-scale

0.479

High

165810

PRS6A
26S proteasome regulatory subunit 6A

1

10

Small-scale

0.479

High

165811

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

2

Small-scale

0.479

High

165812

FLNA
Filamin-A

1

6

Small-scale

0.479

High

165814

TBG1
Tubulin gamma-1 chain

1

5

Small-scale

0.479

High

165817

EF1D
Elongation factor 1-delta

1

3

Small-scale

0.479

High

165819

DNJA1
DnaJ homolog subfamily A member 1

1

6

Small-scale

0.479

High

165822

RS27
Small ribosomal subunit protein eS27

1

2

Small-scale

0.479

High

165823

WASP
Actin nucleation-promoting factor WAS

1

13

Small-scale

0.479

High

165824

PRS6B
26S proteasome regulatory subunit 6B

1

7

Small-scale

0.479

High

165825

CRKL
Crk-like protein

1

8

Small-scale

0.479

High

165826

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

7

Small-scale

0.479

High

165827

SOX2
Transcription factor SOX-2

1

20

Small-scale

0.479

High

165830

STA5B
Signal transducer and activator of transcription 5B

1

7

Small-scale

0.479

High

165831

IMA5
Importin subunit alpha-5

1

5

Small-scale

0.479

High

165834

DCAF7
DDB1- and CUL4-associated factor 7

1

20

Small-scale

0.479

High

165835

WDR5
WD repeat-containing protein 5

1

20

Small-scale

0.479

High

165836

PRS4
26S proteasome regulatory subunit 4

1

7

Small-scale

0.479

High

165837

SMD1
Small nuclear ribonucleoprotein Sm D1

1

3

Small-scale

0.479

High

165838

PRS10
26S proteasome regulatory subunit 10B

1

7

Small-scale

0.479

High

165841

RAE1L
mRNA export factor RAE1

1

20

Small-scale

0.479

High

165842

SMAD3
Mothers against decapentaplegic homolog 3

1

10

Small-scale

0.479

High

165845

ACACA
Acetyl-CoA carboxylase 1

1

1

Small-scale

0.479

High

165846

CBX3
Chromobox protein homolog 3

1

4

Small-scale

0.479

High

165847

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

Small-scale

0.479

High

165848

SMAD4
Mothers against decapentaplegic homolog 4

1

11

Small-scale

0.479

High

165849

TDG
G/T mismatch-specific thymine DNA glycosylase

1

1

Small-scale

0.479

High

165851

SYK
Lysine--tRNA ligase

1

4

Small-scale

0.479

High

165853

RBBP5
Retinoblastoma-binding protein 5

1

20

Small-scale

0.479

High

165854

SMAD2
Mothers against decapentaplegic homolog 2

1

10

Small-scale

0.479

High

165855

SMAD1
Mothers against decapentaplegic homolog 1

1

10

Small-scale

0.479

High

165858

PCID2
PCI domain-containing protein 2

1

1

Small-scale

0.479

High

165860

NIPBL
Nipped-B-like protein

1

20

Small-scale

0.479

High

165862

RS27L
Ribosomal protein eS27-like

1

2

Small-scale

0.479

High

165863

SLN11
Schlafen family member 11

1

3

Small-scale

0.479

High

165865

GEMI5
Gem-associated protein 5

1

17

Small-scale

0.479

High

165867

TNPO1
Transportin-1

1

3

Small-scale

0.479

High

165868

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

11

Small-scale

0.479

High

165870

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

7

Small-scale

0.479

High

165871

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

14

Small-scale

0.479

High

165872

MEP50
Methylosome protein WDR77

1

20

Small-scale

0.479

High

165875

XPO5
Exportin-5

1

4

Small-scale

0.479

High

165877

TSAP1
tRNA selenocysteine 1-associated protein 1

1

7

Small-scale

0.479

High

165878

ANFY1
Rabankyrin-5

1

10

Small-scale

0.479

High

165879

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

12

Small-scale

0.479

High

165880

DDX20
Probable ATP-dependent RNA helicase DDX20

1

14

Small-scale

0.479

High

165884

UBQL1
Ubiquilin-1

1

2

Small-scale

0.479

High

165885

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

1

11

Small-scale

0.479

High

165886

NUDC
Nuclear migration protein nudC

1

1

Small-scale

0.479

High

165799

AKAP8
A-kinase anchor protein 8

1

0

Small-scale

0.458

High

165807

GSTP1
Glutathione S-transferase P

1

0

Small-scale

0.458

High

165813

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

Small-scale

0.458

High

165815

PSA1
Proteasome subunit alpha type-1

1

0

Small-scale

0.458

High

165833

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

165873

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

Small-scale

0.458

High

165883

DNPEP
Aspartyl aminopeptidase

1

0

Small-scale

0.458

High

165800

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

Small-scale

0.437

High

165806

TPM3
Tropomyosin alpha-3 chain

1

2

Small-scale

0.437

High

165818

COR1A
Coronin-1A

1

19

Small-scale

0.437

High

165820

KINH
Kinesin-1 heavy chain

1

5

Small-scale

0.437

High

165829

GUAA
GMP synthase [glutamine-hydrolyzing]

1

2

Small-scale

0.437

High

165843

K1C17
Keratin, type I cytoskeletal 17

1

3

Small-scale

0.437

High

165850

GANAB
Neutral alpha-glucosidase AB

1

1

Small-scale

0.437

High

165852

PDIA6
Protein disulfide-isomerase A6

1

1

Small-scale

0.437

High

165857

P5CR3
Pyrroline-5-carboxylate reductase 3

1

3

Small-scale

0.437

High

165859

SLN13
Schlafen family member 13

1

3

Small-scale

0.437

High

165876

WDR6
tRNA

1

20

Small-scale

0.437

High

165882

PNMA2
Paraneoplastic antigen Ma2

1

2

Small-scale

0.437

High

165803

TIPRL
TIP41-like protein

1

0

Small-scale

0.249

Low

165816

SYVC
Valine--tRNA ligase

1

0

Small-scale

0.249

Low

165828

RPIA
Ribose-5-phosphate isomerase

1

0

Small-scale

0.249

Low

165864

FAD1
FAD synthase

1

0

Small-scale

0.249

Low

165874

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

Small-scale

0.249

Low

165881

NAGK
N-acetyl-D-glucosamine kinase

1

0

Small-scale

0.249

Low

165887

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024