HitPredict

Interactor 1: TBA1A (P68369)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Alpha-tubulin isotype M-alpha-1) (Tubulin alpha-1 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: Tuba1a

Interactor 2: HDAC6 (Q9Z2V5)
Protein deacetylase HDAC6 (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-) (mHDA2)
Gene: HDAC6

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	12486003, 19893491
Identification Methods	enzymatic study, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 451 Mm			1 1149
+	Hs
		1410622 TBA1C_HUMAN (1-451): 0: 722: 98.00		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		997171 TBA4A_HUMAN (1-450): 0: 714: 96.00		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		996878 TBA1B_HUMAN (1-440): 0: 712: 99.55		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		1259543 TBA1A_HUMAN (1-451): 0: 710: 100.00		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		1452288 TBA8_HUMAN (1-440): 0: 701: 90.68		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		457750 TBB5_HUMAN (1-439): 0: 696: 40.77		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		997547 TBB4B_HUMAN (1-437): 0: 694: 40.50		HDAC6_HUMAN (1-1149): 0: 1270: 74.57
+	Hs
		457417 TBB5_HUMAN (1-439): 0: 696: 40.77		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		940914 TBA4A_HUMAN (1-450): 0: 714: 96.00		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Hs
		997319 TBB4B_HUMAN (1-437): 0: 694: 40.50		HDAC1_HUMAN (470-870): 3.76e-156: 475: 20.75
+	Hs
		1259576 TBA1A_HUMAN (1-451): 0: 710: 100.00		HDAC5_HUMAN (439-878): 9.05e-140: 453: 35.89
+	Hs
		457335 TBB5_HUMAN (1-439): 0: 696: 40.77		HDAC4_HUMAN (404-863): 7.4e-141: 455: 36.57
+	Hs
		457777 TBB5_HUMAN (1-439): 0: 696: 40.77		HDAC5_HUMAN (439-878): 9.05e-140: 453: 35.89
+	Hs
		997567 TBB4B_HUMAN (1-437): 0: 694: 40.50		HDAC5_HUMAN (439-878): 9.05e-140: 453: 35.89