HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: JIP3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)
Gene: MAPK8IP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30110629
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0050821 - protein stabilization
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 1336
+	Hs
		229663 EP300_HUMAN (1-2414): 0: 1113: 100.00		JIP4_HUMAN (6-1336): 0: 671: 54.25
+	Hs
		725147 EP300_HUMAN (1-2414): 0: 1113: 100.00		MYH10_HUMAN (243-769): 2.9e-24: 113: 8.89
+	Hs
		998661 EP300_HUMAN (1-2414): 0: 1113: 100.00		ROCK1_HUMAN (2-581): 2.57e-21: 103: 9.37
+	Hs
		724792 EP300_HUMAN (1-2414): 0: 1113: 100.00		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		254474 EP300_HUMAN (1-2414): 0: 1113: 100.00		ROCK2_HUMAN (2-348): 1.31e-13: 78.3: 7.20
+	Hs
		725093 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		725269 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		MYH10_HUMAN (243-769): 2.9e-24: 113: 8.89
+	Hs
		725074 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		551867 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		DESP_HUMAN (27-706): 3.94e-16: 86.8: 11.43
+	Hs
		148838 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		148737 BPTF_HUMAN (2011-2413): 1.11e-14: 82.9: 12.86		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		724946 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		MYH9_HUMAN (228-774): 4.87e-21: 102: 8.04
+	Hs
		148818 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		149109 PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		149481 PCLO_HUMAN (533-1087): 8.45e-12: 73.6: 11.83		CTRO_HUMAN (1-425): 1.46e-17: 91.4: 9.17
+	Hs
		1056879 MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82		MYH14_HUMAN (80-569): 1.98e-11: 71.2: 13.69