HitPredict

Interactor 1: PSA3 (Q09682)
Probable proteasome subunit alpha type-3
Gene: SPAC13C5.01c

Interactor 2: PSB4 (Q09720)
Probable proteasome subunit beta type-4
Gene: SPAC31A2.04c

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24938783
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Sp			1 194
+	Hs
		637323 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB8_HUMAN (2-193): 3.92e-67: 208: 19.27
+	Hs
		637527 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB7_HUMAN (3-188): 5.97e-66: 205: 16.67
+	At
		188701 PSA6B_ARATH (1-243): 5.52e-101: 295: 30.80		PSB7A_ARATH (3-186): 2.32e-66: 206: 16.85
+	Hs
		637328 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB5_HUMAN (2-193): 1.75e-65: 203: 18.75
+	Hs
		637316 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA2_HUMAN (4-192): 1.94e-64: 199: 15.71
+	Hs
		637318 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSA4_HUMAN (3-194): 2.95e-63: 198: 14.80
+	Hs
		637346 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB10_HUMAN (3-192): 2.85e-63: 198: 14.74
+	Hs
		638065 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSB8_HUMAN (2-193): 3.92e-67: 208: 19.27
+	At
		286453 PSA6B_ARATH (1-243): 5.52e-101: 295: 30.80		PSB7B_ARATH (3-186): 1.28e-63: 199: 16.85
+	Hs
		638070 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSB5_HUMAN (2-193): 1.75e-65: 203: 18.75
+	Hs
		637360 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB2_HUMAN (1-193): 6.76e-62: 192: 45.60
+	Hs
		637626 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA2_HUMAN (4-192): 1.94e-64: 199: 15.71
+	Hs
		638061 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSA4_HUMAN (3-194): 2.95e-63: 198: 14.80
+	Hs
		594447 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB1_HUMAN (3-191): 3.42e-33: 120: 23.23
+	Hs
		594450 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSB1_HUMAN (3-191): 3.42e-33: 120: 23.23
+	Ph
		223381 PSA_PYRHO (3-239): 4.78e-100: 293: 40.08		PSB1_PYRHO (3-191): 1.89e-22: 91.2: 20.00
+	Hs
		637326 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB4_HUMAN (3-189): 3.81e-18: 81.1: 18.42
+	Hs
		637359 PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62		PSB3_HUMAN (4-190): 5e-17: 77.3: 18.09
+	Hs
		638068 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSB4_HUMAN (3-189): 3.81e-18: 81.1: 18.42
+	Hs
		638085 PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56		PSB3_HUMAN (4-190): 5e-17: 77.3: 18.09