Protein: A1Z6P8
Exchange protein directly activated by cAMP, isoform E

Gene: A1Z6P8, Epac
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: A1Z6P8

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
GO:0032487 - regulation of Rap protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

52147

O96692
small monomeric GTPase

1

20

High-throughput

0.621

High

52150

KPC3
Protein kinase C

1

8

High-throughput

0.621

High

52155

WEE1
Wee1-like protein kinase

1

1

High-throughput

0.555

High

52159

Q7KMQ6
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.481

High

52164

PLXB
Plexin-B

1

2

High-throughput

0.481

High

52170

RGS
Regulator of G-protein signaling loco

1

1

High-throughput

0.481

High

52175

FOI
Zinc transporter foi

1

1

High-throughput

0.481

High

52141

BOMT2
Bomanin Tailed 2

1

1

High-throughput

0.439

High

52142

B7Z0C5
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

52143

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

1

High-throughput

0.439

High

52144

M9PFR8
Artemis, isoform B

1

3

High-throughput

0.439

High

52145

M9PFW8
Apollo, isoform B

1

3

High-throughput

0.439

High

52146

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.439

High

52148

HSP23
Heat shock protein 23

1

1

High-throughput

0.439

High

52149

UBIQP
Polyubiquitin [Cleaved into: Ubiquitin]

1

5

High-throughput

0.439

High

52151

DYR
Dihydrofolate reductase

1

1

High-throughput

0.439

High

52152

JANA
Sex-regulated protein janus-A

1

1

High-throughput

0.439

High

52153

CNC
Segmentation protein cap'n'collar

1

1

High-throughput

0.439

High

52154

PPIA
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.439

High

52156

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.439

High

52157

TWINE
Cdc25-like protein phosphatase twine

1

2

High-throughput

0.439

High

52158

Q6NLM8
RE56731p

1

1

High-throughput

0.439

High

52160

Q7KSI9
GDT1 family protein

1

1

High-throughput

0.439

High

52162

Q8SXB0
ADAM metallopeptidase with thrombospondin type 1 motif A, isoform B

1

2

High-throughput

0.439

High

52163

Q960E4
SD04973p

1

1

High-throughput

0.439

High

52165

C6A20
Probable cytochrome P450 6a20

1

1

High-throughput

0.439

High

52166

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.439

High

52167

Q9VBE2
RE40518p

1

1

High-throughput

0.439

High

52168

Q9VBN5
60S ribosomal protein L27

1

1

High-throughput

0.439

High

52169

Q9VCB9
FI08802p

1

1

High-throughput

0.439

High

52171

Q9VF51
Aldehyde oxidase 3, isoform A

1

1

High-throughput

0.439

High

52172

Q9VIV5
RT08607p

1

1

High-throughput

0.439

High

52173

Q9VLY0
ATP synthase subunit g

1

1

High-throughput

0.439

High

52174

Q9VPV7
GH09281p

1

1

High-throughput

0.439

High

52176

GALL2
MIP18 family protein galla-2

1

1

High-throughput

0.439

High

52177

Q9VXQ7
GH04557p

1

1

High-throughput

0.439

High

52178

Q9VZK5
GEO11537p1

1

3

High-throughput

0.439

High

52179

Q9W1W8
CG3831 protein

1

1

High-throughput

0.439

High

52161

Q7KTH6
Uncharacterized protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025