Protein: O96692
small monomeric GTPase (EC 3.6.5.2)

Gene: O96692, Rap2l
Organism: Drosophila melanogaster
Interactions: 121
UniProt ID: O96692

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

355913

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

20

High-throughput

0.698

High

57040

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

8

High-throughput

0.625

High

355933

SCRIB
Protein lap4

1

11

High-throughput

0.625

High

355988

Q9VML8
GH01721p

1

4

High-throughput

0.625

High

52147

A1Z6P8
Exchange protein directly activated by cAMP, isoform E

1

20

High-throughput

0.621

High

119956

M9PBW9
Rhea, isoform G

1

20

High-throughput

0.621

High

355957

Q9U4U5
LD16082p

1

20

High-throughput

0.621

High

355968

RGS
Regulator of G-protein signaling loco

1

13

High-throughput

0.621

High

355987

Q9VMF3
Dizzy isoform AII

1

20

High-throughput

0.621

High

356012

Q9W443
Uncharacterized protein, isoform D

1

20

High-throughput

0.621

High

355956

Q9GR11
Ral guanine nucleotide dissociation stimulator-like protein

1

20

High-throughput

0.590

High

304104

RAB7
Ras-related protein Rab7

1

18

High-throughput

0.575

High

355912

RAP1
Ras-related protein Rap1

1

20

High-throughput

0.575

High

355934

Q7KY04
small monomeric GTPase

1

19

High-throughput

0.575

High

355938

Q8IPG1
PDGF- and VEGF-receptor related, isoform B

1

5

High-throughput

0.575

High

356010

Q9W3Q0
FI07418p

1

19

High-throughput

0.575

High

355918

ARF4
ADP ribosylation factor 4

2

18

High-throughput

0.571

High

355926

Q4QQB9
LP21121p

2

1

High-throughput

0.571

High

355927

Q6NP72
GEO09659p1

2

3

High-throughput

0.571

High

355940

Q8IPV3
Uncharacterized protein, isoform A

2

3

High-throughput

0.571

High

355962

KRH2
Krueppel homolog 2

2

3

High-throughput

0.571

High

356009

Q9W3N1
RH59310p

2

9

High-throughput

0.571

High

55863

A1Z9K8
LD13733p

1

15

High-throughput

0.555

High

58604

FEM1B
Protein fem-1 homolog B

1

12

High-throughput

0.555

High

119659

M9PB25
Uncharacterized protein, isoform G

1

1

High-throughput

0.555

High

355924

Q0KI67
Myosin heavy chain-like, isoform G

1

8

High-throughput

0.555

High

355930

Q7K5M6
GH04176p

1

20

High-throughput

0.555

High

355939

Q8IPP3
Canoe, isoform D

1

20

High-throughput

0.555

High

355941

SPRI
Protein sprint

1

20

High-throughput

0.555

High

355972

Q9VFD3
Uncharacterized protein, isoform B

1

20

High-throughput

0.555

High

356008

Q9W2L2
LD27118p

1

17

High-throughput

0.555

High

355974

Q9VFV9
DnaJ-like-2, isoform A

1

7

High-throughput

0.553

High

52344

GDS1
GTPase-GDP dissociation stimulator vimar

1

11

High-throughput

0.541

High

355937

Q8INC3
Myosin heavy chain-like, isoform B

1

8

High-throughput

0.528

High

355946

Q8SX30
RE51969p

1

16

High-throughput

0.528

High

355953

Q95TT5
LD24616p

1

20

High-throughput

0.528

High

355969

Q9VCX2
Locomotion defects, isoform B

1

12

High-throughput

0.528

High

355991

Q9VQU8
Uncharacterized protein, isoform C

1

1

High-throughput

0.528

High

304178

ERD2
ER lumen protein-retaining receptor

2

2

High-throughput

0.521

High

355911

COX2
Cytochrome c oxidase subunit 2

2

2

High-throughput

0.521

High

355920

PRS4
26S proteasome regulatory subunit 4

2

10

High-throughput

0.521

High

355932

Q7KN94
Electron transfer flavoprotein subunit alpha

2

2

High-throughput

0.521

High

355992

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

2

High-throughput

0.521

High

356002

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

9

High-throughput

0.521

High

355976

IPO9
Importin-9

1

2

High-throughput

0.514

High

355994

FRL
Formin-like protein

1

12

High-throughput

0.514

High

355943

ENC
Protein encore

1

3

High-throughput

0.494

High

355973

RDX
Protein roadkill

1

4

High-throughput

0.494

High

356005

Q9W0D3
GH15728p

1

5

High-throughput

0.494

High

194860

CADN
Neural-cadherin

1

5

High-throughput

0.481

High

356001

IF5
Eukaryotic translation initiation factor 5

1

3

High-throughput

0.481

High

356007

Q9W0X0
Scavenger receptor class B member 1

1

5

High-throughput

0.481

High

356000

Q9VWL0
Mec2

1

12

High-throughput

0.479

High

355936

Q8IMI5
FI04474p

1

0

High-throughput

0.460

High

233501

SPY
Protein sprouty

1

8

High-throughput

0.445

High

355914

SYB
Synaptobrevin

1

20

High-throughput

0.445

High

355915

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

12

High-throughput

0.445

High

355922

ARL2
ADP-ribosylation factor-like protein 2

1

18

High-throughput

0.445

High

355923

ROP
Protein ROP

1

13

High-throughput

0.445

High

355928

Q7K0X9
LD23667p

1

20

High-throughput

0.445

High

355949

Q8T8W3
AT21416p

1

9

High-throughput

0.445

High

355955

Q960F6
SD03655p

1

2

High-throughput

0.445

High

355978

ARL8
ADP-ribosylation factor-like protein 8

1

18

High-throughput

0.445

High

355982

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

11

High-throughput

0.445

High

355984

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

1

High-throughput

0.445

High

355995

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

3

High-throughput

0.445

High

356013

Q9W4N8
LD30122p

1

8

High-throughput

0.445

High

197554

PAX6
Paired box protein Pax-6

1

6

High-throughput

0.439

High

355916

HMOC
Homeotic protein ocelliless

1

3

High-throughput

0.439

High

355925

Q32KD4
Protein argonaute-1

1

1

High-throughput

0.439

High

355935

Q7PLB8
Fatty acid synthase

1

4

High-throughput

0.439

High

355970

ARP5
Actin-related protein 5

1

4

High-throughput

0.439

High

355971

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

4

High-throughput

0.439

High

355990

Q9VPV8
IA-2 protein tyrosine phosphatase, isoform C

1

9

High-throughput

0.439

High

355979

BERO
UPAR/Ly6 domain-containing protein bero

1

0

High-throughput

0.438

High

52632

A1Z729
NADP-retinol dehydrogenase

1

8

High-throughput

0.437

High

355950

VDAC
Voltage-dependent anion-selective channel

1

12

High-throughput

0.437

High

355951

LDH
L-lactate dehydrogenase

1

5

High-throughput

0.437

High

355993

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.426

High

355944

Q8MZH8
Fatty acid synthase

1

4

High-throughput

0.417

High

355917

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

7

High-throughput

0.407

High

355919

COPB
Coatomer subunit beta

1

3

High-throughput

0.407

High

355921

TCPG
T-complex protein 1 subunit gamma

1

9

High-throughput

0.407

High

355929

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.407

High

355931

Q7KMQ0
26S proteasome regulatory subunit 7

1

8

High-throughput

0.407

High

355942

Q8MRW1
SD19278p

1

2

High-throughput

0.407

High

355945

Q8STG9
DSec61alpha

1

3

High-throughput

0.407

High

355954

Q960C7
NADP-retinol dehydrogenase

1

8

High-throughput

0.407

High

355958

Q9V3V6
26S proteasome regulatory complex subunit p50

1

13

High-throughput

0.407

High

355959

Q9V405
26S proteasome regulatory subunit 6B

1

5

High-throughput

0.407

High

355961

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.407

High

355963

Q9V9Q4
LD43819p

1

3

High-throughput

0.407

High

355966

Q9VBU5
3-dehydrosphinganine reductase

1

5

High-throughput

0.407

High

355981

Q9VK46
Protein YIPF

1

7

High-throughput

0.407

High

355983

NFS1
Cysteine desulfurase, mitochondrial

1

2

High-throughput

0.407

High

355985

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

2

High-throughput

0.407

High

355996

Q9VV75
AT02348p

1

3

High-throughput

0.407

High

355997

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.407

High

355999

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

356004

Q9VZL3
very-long-chain enoyl-CoA reductase

1

4

High-throughput

0.407

High

356006

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

4

High-throughput

0.407

High

356011

Q9W414
Regulatory particle triple-A ATPase 4

1

8

High-throughput

0.407

High

355965

Q9VBF0
Ras modification protein ERF4

2

0

High-throughput

0.298

High

355980

Q9VJD1
Glucosidase 2 subunit beta

2

0

High-throughput

0.298

High

355998

Q9VW70
FI21813p1

2

0

High-throughput

0.298

High

355947

Q8SX78
LD05679p

1

0

High-throughput

0.282

High

356003

Q9VZF0
LD44732p

1

0

High-throughput

0.265

Low

52824

COIL
Coilin

1

0

High-throughput

0.251

Low

55189

A1Z991
Glial lazarillo, isoform A

1

0

High-throughput

0.251

Low

355960

Q9V414
LD36341p

1

0

High-throughput

0.251

Low

355964

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.251

Low

355975

Q9VGE9
GH11519p

1

0

High-throughput

0.251

Low

355977

Q9VGT8
UDP-glucuronosyltransferase

1

0

High-throughput

0.251

Low

356015

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.251

Low

355948

Q8SZJ6
GH23107p

1

0

High-throughput

0.238

Low

2698

A0A0B4LFU9
Anastral spindle 2, isoform B

1

0

High-throughput

0.232

Low

355952

Q95R82
SD02746p

1

0

High-throughput

0.232

Low

355967

Q9VCF8
LD23561p

1

0

High-throughput

0.232

Low

355986

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

355989

Q9VMX4
AT19154p

1

0

High-throughput

0.232

Low

356014

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025