Protein: Q8SXM8
Lysine--tRNA ligase (EC 6.1.1.6) (Lysyl-tRNA synthetase)

Gene: Q8SXM8, LysRS
Organism: Drosophila melanogaster
Interactions: 59
UniProt ID: Q8SXM8

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004824 - lysine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1343836

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

5

High-throughput

0.575

High

1343827

Q9VLS7
LD21067p

1

3

High-throughput

0.484

High

1343815

WARTS
Serine/threonine-protein kinase Warts

1

4

High-throughput

0.479

High

875107

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.464

High

929210

FOJO
Extracellular serine/threonine protein kinase four-jointed

1

0

High-throughput

0.458

High

53135

A1Z7K8
AaRS-interacting multifunctional protein 1

1

8

High-throughput

0.445

High

746390

GPRK2
G protein-coupled receptor kinase 2

1

2

High-throughput

0.445

High

1177458

Q29QQ9
Ribosomal RNA-processing protein 42

1

1

High-throughput

0.445

High

1343817

DMDA
Dystrophin, isoforms A/C/F/G/H

1

1

High-throughput

0.445

High

1343819

Y6693
J domain-containing protein CG6693

1

2

High-throughput

0.445

High

1343820

Q9VGZ2
FI06805p

1

1

High-throughput

0.445

High

1343823

RM13
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.445

High

1343829

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

2

High-throughput

0.445

High

1343832

Q9VSD6
D-Importin 7/RanBP7

1

2

High-throughput

0.445

High

1343834

Q9VUH8
Survival of motor neuron-related-splicing factor 30

1

2

High-throughput

0.445

High

1343835

RM39
Large ribosomal subunit protein mL39

1

4

High-throughput

0.445

High

1343838

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.445

High

1343847

SYQ
Probable glutamine--tRNA ligase

1

14

High-throughput

0.445

High

460076

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.442

High

1343841

Q9W0L7
ubiquitinyl hydrolase 1

1

7

High-throughput

0.442

High

1052557

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.426

High

1265947

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

0

High-throughput

0.426

High

1305000

EXOS3
Exosome complex component RRP40

1

0

High-throughput

0.426

High

1343813

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

0

High-throughput

0.426

High

1343825

Q9VL60
RE01590p

1

0

High-throughput

0.426

High

1343845

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.426

High

1343848

Q9Y134
RNA helicase

1

0

High-throughput

0.426

High

56841

A1ZAK3
Protein DEK

1

2

High-throughput

0.407

High

232175

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.407

High

925804

SET
Protein SET

1

1

High-throughput

0.407

High

1264889

Q7K1Q7
Ribosome assembly factor mrt4

1

1

High-throughput

0.407

High

1343814

Q9VA36
CIN85 and CD2AP related, isoform C

1

2

High-throughput

0.407

High

1343816

Q9VC93
Exosome complex exonuclease RRP44

1

1

High-throughput

0.407

High

1343824

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.407

High

1343826

Q9VLB7
Rab GDP dissociation inhibitor

1

1

High-throughput

0.407

High

1343831

Q9VQI5
Interferon-related developmental regulator 1

1

1

High-throughput

0.407

High

1343837

RUXG
Probable small nuclear ribonucleoprotein G

1

3

High-throughput

0.407

High

1343839

Q9VYT3
FI23714p1

1

2

High-throughput

0.407

High

1343846

Q9Y0Y5
Coatomer subunit epsilon

1

1

High-throughput

0.407

High

1202966

Q5BI03
LD02690p

1

0

High-throughput

0.265

Low

54881

A1Z909
LD11307p

1

0

High-throughput

0.232

Low

231843

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

0

High-throughput

0.232

Low

847874

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.232

Low

1304740

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.232

Low

1343229

Q8SWS7
Nucleolar protein 12

1

0

High-throughput

0.232

Low

1343809

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.232

Low

1343810

Q9I7N2
Nucleoporin NUP42

1

0

High-throughput

0.232

Low

1343811

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

0

High-throughput

0.232

Low

1343812

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.232

Low

1343818

RRP15
RRP15-like protein

1

0

High-throughput

0.232

Low

1343821

Q9VHT5
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.232

Low

1343822

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.232

Low

1343828

RUXE
Probable small nuclear ribonucleoprotein E

1

0

High-throughput

0.232

Low

1343830

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1343833

Q9VT38
GH03795p

1

0

High-throughput

0.232

Low

1343840

Q9VZC8
GEO12024p1

1

0

High-throughput

0.232

Low

1343842

Q9W0U6
Sulfatase-modifying factor enzyme-like domain-containing protein

1

0

High-throughput

0.232

Low

1343843

Q9W108
FI01540p

1

0

High-throughput

0.232

Low

1343844

Q9W224
Novel spermatogenesis regulator, isoform A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025