Protein: Q9VC93
Exosome complex exonuclease RRP44 (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)

Gene: Q9VC93, Dis3
Organism: Drosophila melanogaster
Interactions: 114
UniProt ID: Q9VC93

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000278 - mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1177474

Q29QQ9
Ribosomal RNA-processing protein 42

4

19

Small-scale

0.867

High

1345951

Q8T4A9
Exosome complex component RRP45

3

20

Small-scale

0.817

High

1470073

Q9VGZ2
FI06805p

3

16

Small-scale

0.817

High

1470084

Q9VK19
FI07225p

3

19

Small-scale

0.817

High

1470103

Q9VW53
FI01414p

3

19

Small-scale

0.817

High

1470072

EXOSX
Exosome complex component 10 homolog

4

5

Small-scale

0.672

High

1470085

Q9VKJ4
Csl4

4

4

Small-scale

0.672

High

1470116

Q9W1M9
Exosome complex component RRP4

4

9

Small-scale

0.672

High

1305014

EXOS3
Exosome complex component RRP40

3

4

Small-scale

0.633

High

1465444

Q9V455
Importin subunit alpha

2

2

Small-scale

0.584

High

1470105

Q9VXL4
Nuclear nucleic acid-binding protein C1D

2

0

Small-scale

0.559

High

1470121

SPT6H
Transcription elongation factor SPT6

1

0

Small-scale

0.546

High

145750

MOF
Histone acetyltransferase MOF

1

0

Small-scale

0.458

High

896162

MSL3
Protein male-specific lethal-3

1

0

Small-scale

0.458

High

54889

A1Z909
LD11307p

1

2

High-throughput

0.445

High

231850

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

1

High-throughput

0.445

High

235136

O46307
EG:8D8.4 protein

1

1

High-throughput

0.445

High

356835

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

2

High-throughput

0.445

High

426748

HP1
Heterochromatin protein 1

1

2

High-throughput

0.445

High

561817

MODU
DNA-binding protein modulo

1

3

High-throughput

0.445

High

654885

MA205
205 kDa microtubule-associated protein

1

1

High-throughput

0.445

High

1050915

SSRP1
FACT complex subunit Ssrp1

1

1

High-throughput

0.445

High

1237369

Q6NQY9
ATP-dependent RNA helicase

1

9

High-throughput

0.445

High

1264905

Q7K1Q7
Ribosome assembly factor mrt4

1

3

High-throughput

0.445

High

1265957

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

2

High-throughput

0.445

High

1273697

Q7PLL3
Eukaryotic initiation factor 4B

1

2

High-throughput

0.445

High

1343261

Q8SWT2
RNA helicase

1

2

High-throughput

0.445

High

1377777

EBI
F-box-like/WD repeat-containing protein ebi

1

4

High-throughput

0.445

High

1463904

WDS
Protein will die slowly

1

3

High-throughput

0.445

High

1465906

RU2A
Probable U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.445

High

1466477

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

1

High-throughput

0.445

High

1470074

Q9VH81
protein-serine/threonine phosphatase

1

1

High-throughput

0.445

High

1470079

Q9VHT5
Large ribosomal subunit protein uL1m

1

2

High-throughput

0.445

High

1470110

Q9VZ88
AT07585p

1

2

High-throughput

0.445

High

1470119

Q9W3J4
LD35215p

1

1

High-throughput

0.445

High

1470123

NSUN2
tRNA

1

2

High-throughput

0.445

High

1470127

Q9Y134
RNA helicase

1

8

High-throughput

0.445

High

56865

A1ZAK3
Protein DEK

1

0

High-throughput

0.426

High

718347

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.426

High

847896

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.426

High

887804

MCM2
DNA replication licensing factor Mcm2

1

0

High-throughput

0.426

High

925825

SET
Protein SET

1

0

High-throughput

0.426

High

1266550

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

1304781

Q8IPU8
BNIP3, isoform B

1

0

High-throughput

0.426

High

1306335

SPT16
FACT complex subunit spt16

1

0

High-throughput

0.426

High

1440142

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.426

High

1470075

Q9VHM3
LD30467p

1

0

High-throughput

0.426

High

1470080

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.426

High

1470083

RAGP1
Ran GTPase-activating protein

1

0

High-throughput

0.426

High

1470094

Q9VPM0
GH06023p

1

0

High-throughput

0.426

High

1470096

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.426

High

1470100

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

1470104

RUXG
Probable small nuclear ribonucleoprotein G

1

0

High-throughput

0.426

High

1470109

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.426

High

1470112

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.426

High

1470115

Q9W1M6
Regulatory protein zeste

1

0

High-throughput

0.426

High

1470117

Q9W224
Novel spermatogenesis regulator, isoform A

1

0

High-throughput

0.426

High

1470120

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.426

High

1470122

Q9W4J4
GM14292p

1

0

High-throughput

0.426

High

1470124

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.426

High

1196573

Q4V5H1
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.407

High

1264034

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.407

High

1303656

Q8IN95
Nuclear migration protein nudC

1

1

High-throughput

0.407

High

1343816

Q8SXM8
Lysine--tRNA ligase

1

1

High-throughput

0.407

High

1345070

WDR55
WD repeat-containing protein 55 homolog

1

5

High-throughput

0.407

High

1463442

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.407

High

1465257

PDIA6
Protein disulfide-isomerase A6 homolog

1

1

High-throughput

0.407

High

1466148

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

1

High-throughput

0.407

High

1470077

RM19
Large ribosomal subunit protein bL19m

1

1

High-throughput

0.407

High

1470081

Q9VIH1
CG9273 protein

1

1

High-throughput

0.407

High

1470086

WDR12
Ribosome biogenesis protein WDR12 homolog

1

3

High-throughput

0.407

High

1470087

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.407

High

1470088

Q9VL60
RE01590p

1

1

High-throughput

0.407

High

1470091

Q9VNX6
LD06749p

1

1

High-throughput

0.407

High

1470097

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

1

High-throughput

0.407

High

1470102

Q9VVI0
SD09427p

1

3

High-throughput

0.407

High

1470107

Q9VYQ9
Pleiotropic regulator 1

1

4

High-throughput

0.407

High

1470108

Q9VYT3
FI23714p1

1

1

High-throughput

0.407

High

1470114

Q9W108
FI01540p

1

3

High-throughput

0.407

High

756984

FAS2
Fasciclin-2

2

0

High-throughput

0.328

High

1470113

Q9VZR0
SD05789p2

1

0

High-throughput

0.265

Low

53156

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

54982

A1Z917
PiggyBac transposable element-derived protein domain-containing protein

1

0

High-throughput

0.232

Low

231996

O44226
Elongin-B

1

0

High-throughput

0.232

Low

875543

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

1

0

High-throughput

0.232

Low

1019503

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.232

Low

1195961

Q4QQ70
IP09819p

1

0

High-throughput

0.232

Low

1261408

Q7JQT8
LD41464p

1

0

High-throughput

0.232

Low

1264283

Q7K0L8
FLICE-associated huge protein, isoform A

1

0

High-throughput

0.232

Low

1305527

Q8IQI3
Uncharacterized protein, isoform B

1

0

High-throughput

0.232

Low

1305931

Q8IR42
Drop dead

1

0

High-throughput

0.232

Low

1320846

Q8MMD2
Epidermal growth factor receptor pathway substrate clone 15, isoform B

1

0

High-throughput

0.232

Low

1321789

Q8MT77
LD28489p

1

0

High-throughput

0.232

Low

1343234

Q8SWS7
Nucleolar protein 12

1

0

High-throughput

0.232

Low

1463327

Q9V3D8
GH27579p

1

0

High-throughput

0.232

Low

1466648

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.232

Low

1468783

Q9VB04
Protein CASC3

1

0

High-throughput

0.232

Low

1469589

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1470076

Q9VHN4
GH14121p

1

0

High-throughput

0.232

Low

1470078

Q9VHR5
Veneno

1

0

High-throughput

0.232

Low

1470082

NESD
Protein nessun dorma

1

0

High-throughput

0.232

Low

1470089

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

0

High-throughput

0.232

Low

1470090

Q9VNF6
Metastasis-associated protein MTA3

1

0

High-throughput

0.232

Low

1470092

Q9VNZ3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.232

Low

1470093

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.232

Low

1470095

Q9VQS4
Spindly

1

0

High-throughput

0.232

Low

1470098

Q9VT38
GH03795p

1

0

High-throughput

0.232

Low

1470099

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.232

Low

1470101

Q9VVF8
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1470106

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1470111

Q9VZC8
GEO12024p1

1

0

High-throughput

0.232

Low

1470118

Q9W323
Tyrosine-protein phosphatase non-receptor type 9

1

0

High-throughput

0.232

Low

1470125

Q9Y0Y5
Coatomer subunit epsilon

1

0

High-throughput

0.232

Low

1470126

SYQ
Probable glutamine--tRNA ligase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025