Protein: ECR
Ecdysone receptor (20-hydroxy-ecdysone receptor) (20E receptor) (EcRH) (Ecdysteroid receptor) (Nuclear receptor subfamily 1 group H member 1)

Gene: ECR
Organism: Drosophila melanogaster
Interactions: 107
UniProt ID: P34021

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

589658

USP
Protein ultraspiracle

16

20

Small-scale

0.982

High

709176

CSN2
COP9 signalosome complex subunit 2

3

8

Small-scale

0.655

High

709213

Q9VYW2
FI10506p

2

20

Small-scale

0.640

High

709164

RIG
Protein rigor mortis

2

3

Small-scale

0.624

High

709172

TRR
Histone-lysine N-methyltransferase trr

2

20

Small-scale

0.624

High

558425

7UP1
Steroid receptor seven-up, isoforms B/C

1

20

Small-scale

0.621

High

709141

ECR
Ecdysone receptor

1

19

Small-scale

0.621

High

709145

HR38
Probable nuclear hormone receptor HR38

1

19

Small-scale

0.621

High

709174

Q8WS79
Estrogen-related receptor splice variant

1

19

Small-scale

0.618

High

332740

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

2

20

Small-scale

0.601

High

709177

ARI1
E3 ubiquitin-protein ligase ariadne-1

1

8

Small-scale

0.573

High

709171

Q8IRB4
Diabetes and obesity regulated, isoform C

2

0

Small-scale

0.559

High

709185

Q9NIR3
CRC-B

1

11

Small-scale

0.552

High

709209

CDK8
Cyclin-dependent kinase 8

1

17

Small-scale

0.552

High

709214

MED14
Mediator of RNA polymerase II transcription subunit 14

1

20

Small-scale

0.552

High

709151

TRF
TBP-related factor

1

6

High-throughput

0.541

High

709175

NFKB1
Nuclear factor NF-kappa-B p110 subunit

1

20

High-throughput

0.541

High

631287

BRM
ATP-dependent helicase brm

1

20

Small-scale

0.515

High

709150

CP190
Centrosome-associated zinc finger protein Cp190

1

9

Small-scale

0.515

High

709165

NELFA
Negative elongation factor A

1

20

Small-scale

0.515

High

709168

OSA
Trithorax group protein osa

1

20

Small-scale

0.515

High

709188

SPT5H
Transcription elongation factor SPT5

1

19

Small-scale

0.515

High

709193

Q9VF03
Brahma associated protein 155 kDa

1

20

Small-scale

0.515

High

284503

E2F2
Transcription factor E2F2

1

5

High-throughput

0.508

High

332657

PLK4
Serine/threonine-protein kinase PLK4

1

8

High-throughput

0.508

High

618428

CDK2
Cyclin-dependent kinase 2

1

8

High-throughput

0.508

High

709143

CDK5
Cyclin-dependent kinase 5 homolog

1

10

High-throughput

0.508

High

709156

Q7K306
Cyclin-dependent kinase 4, isoform A

1

8

High-throughput

0.508

High

709158

Q7KPG8
CDK-activating kinase assembly factor MAT1

1

1

High-throughput

0.508

High

709169

AKT1
RAC serine/threonine-protein kinase

1

17

High-throughput

0.508

High

709180

CYCG
Cyclin G

1

1

High-throughput

0.508

High

709181

Q961D1
Cyclin K, isoform A

1

17

High-throughput

0.508

High

709190

Q9V9R2
Cullin 2, isoform A

1

10

High-throughput

0.508

High

709192

Q9VDE3
LD08669p

1

16

High-throughput

0.508

High

709198

PAK
Serine/threonine-protein kinase Pak

1

10

High-throughput

0.508

High

709216

Q9W1J7
SKP1 component POZ domain-containing protein

1

2

High-throughput

0.508

High

115053

M9PE30
Transgelin

1

10

Small-scale

0.504

High

709146

FKB39
39 kDa FK506-binding nuclear protein

1

6

Small-scale

0.504

High

709148

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.501

High

709218

EXOC5
Exocyst complex component 5

1

1

High-throughput

0.494

High

709149

Q24294
Dcdrk kinase

1

15

High-throughput

0.494

High

709163

Q86BS3
Chromator, isoform A

1

0

Small-scale

0.493

High

540474

CCNA
G2/mitotic-specific cyclin-A

1

0

High-throughput

0.486

High

283945

O76513
Cyclin-H

1

19

High-throughput

0.481

High

577335

PTC
Protein patched

1

1

High-throughput

0.481

High

709153

Q5U0V6
protein-tyrosine-phosphatase

1

8

High-throughput

0.481

High

709154

Q7JNL9
Dacapo

1

1

High-throughput

0.481

High

709157

Q7K3Q3
Regulatory protein zeste

1

3

High-throughput

0.481

High

709160

Q7KUZ5
Cyclin D, isoform D

1

8

High-throughput

0.481

High

709196

Q9VHB7
LD22928p

1

5

High-throughput

0.481

High

709208

Q9VSE6
DNA 3'-5' helicase

1

20

High-throughput

0.481

High

53341

TPR
Nucleoprotein TPR

1

20

Small-scale

0.479

High

68992

A8WHL4
Bonus, isoform B

1

20

Small-scale

0.479

High

114486

M9PCJ7
Utx histone demethylase, isoform E

1

17

Small-scale

0.479

High

115933

M9PGZ8
Smrter, isoform G

1

20

Small-scale

0.479

High

115987

M9PH39
histone acetyltransferase

1

20

Small-scale

0.479

High

505049

HSP7D
Heat shock 70 kDa protein cognate 4

1

19

Small-scale

0.479

High

625698

CCNC
Cyclin-C

1

18

Small-scale

0.479

High

709152

YAP1
Transcriptional coactivator yorkie

1

13

Small-scale

0.479

High

709159

MED13
Mediator of RNA polymerase II transcription subunit 13

1

8

Small-scale

0.479

High

709167

FRU
Sex determination protein fruitless

1

20

Small-scale

0.479

High

709173

Q8T0D3
Dek, isoform B

1

6

Small-scale

0.479

High

709186

KDM4A
Probable lysine-specific demethylase 4A

1

14

Small-scale

0.479

High

709187

CSN4
COP9 signalosome complex subunit 4

1

7

Small-scale

0.479

High

709189

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

Small-scale

0.479

High

709191

NUP98
Nuclear pore complex protein Nup98-Nup96

1

20

Small-scale

0.479

High

709194

Q9VGW7
Arginine methyltransferase 1

1

20

Small-scale

0.479

High

709195

CARM1
Probable histone-arginine methyltransferase CARMER

1

20

Small-scale

0.479

High

709202

Q9VLX0
Lysine ketoglutarate reductase/saccharopine dehydrogenase, isoform A

1

1

Small-scale

0.479

High

709204

MED27
Mediator of RNA polymerase II transcription subunit 27

1

3

Small-scale

0.479

High

709205

MED1
Mediator of RNA polymerase II transcription subunit 1

1

20

Small-scale

0.479

High

709206

Q9VS55
CTCF

1

14

Small-scale

0.479

High

709211

MED12
Mediator of RNA polymerase II transcription subunit 12

1

20

Small-scale

0.479

High

709212

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

15

Small-scale

0.479

High

709215

Q9W1H0
HL01030p

1

20

Small-scale

0.479

High

709219

CSN5
COP9 signalosome complex subunit 5

1

12

Small-scale

0.479

High

709220

MED15
Mediator of RNA polymerase II transcription subunit 15

1

20

Small-scale

0.479

High

709161

SP42D
Serine protease inhibitor 42Dd

1

9

High-throughput

0.464

High

709199

Q9VIF2
GM01519p

1

1

High-throughput

0.464

High

709200

Q9VIH1
Replication factor A protein 2

1

2

High-throughput

0.464

High

709203

POLZ2
DNA polymerase zeta subunit 2

1

1

High-throughput

0.464

High

112271

M9MRJ8
Taiman, isoform E

1

0

Small-scale

0.458

High

2281

A0A0B4KEQ7
Regulatory protein zeste

1

3

High-throughput

0.457

High

2571

A0A0B4KGZ0
Methyl-CpG binding domain protein-like, isoform C

1

5

High-throughput

0.457

High

184390

O17144
Cyclin-H

1

19

High-throughput

0.457

High

709144

MNB
Serine/threonine-protein kinase minibrain

1

18

High-throughput

0.457

High

709147

P91668
Cyclin-dependent kinase inhibitor Dacapo

1

1

High-throughput

0.457

High

709178

Q95R37
SD10969p

1

12

High-throughput

0.457

High

709182

Q961G6
Cyclin-Q

1

17

High-throughput

0.457

High

709183

Q9GTQ8
Cyclin D

1

8

High-throughput

0.457

High

709184

Q9NH11
DNA 3'-5' helicase

1

20

High-throughput

0.457

High

709201

Q9VLW7
protein-tyrosine-phosphatase

1

7

High-throughput

0.457

High

709207

AKIRN
Akirin

1

1

Small-scale

0.457

High

709170

Q8IQX8
histidine--tRNA ligase

1

1

High-throughput

0.445

High

709197

JHD1
JmjC domain-containing histone demethylation protein 1

1

14

High-throughput

0.445

High

709210

Q9VV77
Lethal

1

17

High-throughput

0.445

High

66114

A8JUS8
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

81352

B7Z0M0
FI17308p1

1

1

High-throughput

0.439

High

709142

PLU
DNA replication inhibitor plutonium

1

20

High-throughput

0.439

High

709155

Q7JQF6
HL05804p

1

0

High-throughput

0.426

High

709162

Q868J0
PLU

1

20

High-throughput

0.417

High

709217

Q9W5G0
LD08762p

1

1

High-throughput

0.417

High

81155

LINT
Serine protease filzig

1

3

High-throughput

0.407

High

285093

IPYR
Inorganic pyrophosphatase

1

0

Small-scale

0.391

High

709179

Q95RS0
LD10926p

1

0

High-throughput

0.365

High

709166

Q8IGE8
RH36596p

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024