Protein: SETB1
Histone-lysine N-methyltransferase eggless (EC 2.1.1.355) (SETDB1 homolog)

Gene: SETB1, egg
Organism: Drosophila melanogaster
Interactions: 36
UniProt ID: Q32KD2

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1181099

Q7KMH9
BcDNA.LD26050

5

10

Small-scale

0.699

High

1181096

Q5LJQ3
Uncharacterized protein, isoform C

2

3

High-throughput

0.677

High

1181100

Q8MRI3
LD29015p

2

3

High-throughput

0.665

High

381705

H3
Histone H3

1

20

Small-scale

0.647

High

1181101

ASH2
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

5

Small-scale

0.618

High

426670

HP1
Heterochromatin protein 1

2

20

Small-scale

0.584

High

1181116

Q9XYM5
LD27861p

2

5

Small-scale

0.584

High

1172337

HR78
Nuclear hormone receptor HR78

1

11

High-throughput

0.541

High

1181104

SPIR
Protein spire

1

0

Small-scale

0.529

High

95211

E1JIH4
Uncharacterized protein, isoform D

1

0

High-throughput

0.518

High

1181107

Q9VHF4
Doctor no, isoform B

1

0

High-throughput

0.518

High

56353

ZASP
PDZ and LIM domain protein Zasp

1

1

Small-scale

0.504

High

1181113

POF
Protein painting of fourth

1

0

Small-scale

0.493

High

144536

HOW
Protein held out wings

1

0

High-throughput

0.486

High

628532

USP
Protein ultraspiracle

1

12

Small-scale

0.481

High

1181098

UBC10
Ubiquitin-conjugating enzyme E2-18 kDa

1

3

Small-scale

0.481

High

1181110

Q9VRZ3
Zinc carboxypeptidase A 1

1

1

Small-scale

0.481

High

1181111

Q9VUE5
LD17962p

1

1

High-throughput

0.481

High

356335

O97102
Small ubiquitin-related modifier

1

4

Small-scale

0.479

High

731973

CROC
Fork head domain-containing protein crocodile

1

1

Small-scale

0.479

High

1069288

Q0E8J0
MOG interacting and ectopic P-granules protein 1

1

2

Small-scale

0.479

High

1181103

Q961B8
ADD domain-containing protein 1, isoform B

1

13

Small-scale

0.479

High

1181105

WDS
Protein will die slowly

1

4

Small-scale

0.479

High

1181106

Q9VCU6
Heterochromatin protein 1c

1

20

Small-scale

0.479

High

1181115

Q9W396
FI06908p

1

20

Small-scale

0.479

High

1172147

DYL1
Dynein light chain 1, cytoplasmic

1

0

Small-scale

0.460

High

1181108

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

1181114

Q9W1K4
Egalitarian, isoform B

1

0

High-throughput

0.458

High

1172585

Q24156
Transcription factor

1

1

High-throughput

0.457

High

616532

ARM
Armadillo segment polarity protein

1

1

High-throughput

0.445

High

652026

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

1

Small-scale

0.439

High

1181112

Q9VY76
AMP deaminase

1

0

Small-scale

0.288

High

1181095

Q4V5L1
IP07030p

1

0

High-throughput

0.265

Low

1181097

Q7JRQ4
AT16918p

1

0

High-throughput

0.265

Low

1181109

Q9VLT3
LD23292p

1

0

Small-scale

0.251

Low

1181102

Q95RF6
LD34461p

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025