Protein: RPC1
DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160)

Gene: RPC1, POLR3A
Organism: Homo sapiens
Interactions: 133
UniProt ID: O14802

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

156009

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

5

10

High-throughput

0.927

High

156073

RPC2
DNA-directed RNA polymerase III subunit RPC2

5

20

Small-scale

0.912

High

155988

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

14

High-throughput

0.909

High

155960

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

18

High-throughput

0.903

High

156086

RPC8
DNA-directed RNA polymerase III subunit RPC8

4

12

High-throughput

0.895

High

156057

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

3

1

High-throughput

0.871

High

156062

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

3

1

High-throughput

0.861

High

156085

RPC10
DNA-directed RNA polymerase III subunit RPC10

3

20

High-throughput

0.861

High

156005

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

10

Small-scale

0.847

High

155962

RPC7
DNA-directed RNA polymerase III subunit RPC7

2

1

Small-scale

0.789

High

155968

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

3

High-throughput

0.789

High

156007

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

9

High-throughput

0.789

High

155987

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

18

High-throughput

0.754

High

156037

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

3

High-throughput

0.754

High

156072

RPC5
DNA-directed RNA polymerase III subunit RPC5

6

3

Small-scale

0.738

High

155980

RPC4
DNA-directed RNA polymerase III subunit RPC4

6

3

Small-scale

0.733

High

156066

RPAP3
RNA polymerase II-associated protein 3

5

7

High-throughput

0.709

High

156012

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

4

8

High-throughput

0.702

High

156074

PIHD1
PIH1 domain-containing protein 1

4

3

High-throughput

0.694

High

156058

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.691

High

156063

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.691

High

155999

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

8

High-throughput

0.667

High

156014

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

11

High-throughput

0.667

High

156023

TEBP
Prostaglandin E synthase 3

3

1

High-throughput

0.667

High

156035

SKAP1
Src kinase-associated phosphoprotein 1

3

5

High-throughput

0.667

High

156076

UXT
Protein UXT

3

2

High-throughput

0.667

High

156082

RUVB2
RuvB-like 2

3

9

High-throughput

0.667

High

156079

PFD2
Prefoldin subunit 2

3

3

High-throughput

0.656

High

155972

RMP
Unconventional prefoldin RPB5 interactor 1

3

2

Small-scale

0.640

High

156008

EVA1C
Protein eva-1 homolog C

3

0

High-throughput

0.638

High

155997

CADH5
Cadherin-5

2

1

High-throughput

0.628

High

156065

ASB7
Ankyrin repeat and SOCS box protein 7

2

2

High-throughput

0.628

High

156083

RUVB1
RuvB-like 1

2

9

High-throughput

0.628

High

155964

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

8

High-throughput

0.618

High

155973

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

11

High-throughput

0.618

High

155994

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

11

High-throughput

0.618

High

155996

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

20

High-throughput

0.618

High

156000

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

20

High-throughput

0.618

High

156006

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

11

High-throughput

0.618

High

156013

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

12

High-throughput

0.618

High

156017

TF2B
Transcription initiation factor IIB

1

5

Small-scale

0.618

High

156061

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

3

High-throughput

0.618

High

156068

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

20

High-throughput

0.618

High

156075

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

20

High-throughput

0.618

High

156069

GPN1
GPN-loop GTPase 1

2

9

High-throughput

0.611

High

156080

GPN3
GPN-loop GTPase 3

3

9

High-throughput

0.609

High

155982

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

11

High-throughput

0.575

High

155975

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.571

High

156055

PKP2
Plakophilin-2

1

2

Small-scale

0.561

High

156010

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

High-throughput

0.541

High

156018

EWS
RNA-binding protein EWS

1

5

High-throughput

0.541

High

156087

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.541

High

61740

BDP1
Transcription factor TFIIIB component B'' homolog

1

2

High-throughput

0.536

High

155959

ML12B
Myosin regulatory light chain 12B

1

1

High-throughput

0.536

High

155989

CSK22
Casein kinase II subunit alpha'

1

12

High-throughput

0.536

High

155990

TBP
TATA-box-binding protein

1

4

High-throughput

0.536

High

155991

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

2

High-throughput

0.536

High

155992

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

156001

GRK6
G protein-coupled receptor kinase 6

1

2

High-throughput

0.536

High

156004

JAK3
Tyrosine-protein kinase JAK3

1

5

High-throughput

0.536

High

156015

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.536

High

156020

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.536

High

156043

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

1

High-throughput

0.536

High

156044

TRI52
E3 ubiquitin-protein ligase TRIM52

1

2

High-throughput

0.536

High

156048

AURKB
Aurora kinase B

1

2

High-throughput

0.536

High

156054

TESK2
Dual specificity testis-specific protein kinase 2

1

1

High-throughput

0.536

High

156050

DAA10
Dynein axonemal assembly factor 10

2

2

High-throughput

0.533

High

121891

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.513

High

155965

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.513

High

155969

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.513

High

155977

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

155978

HG2A
HLA class II histocompatibility antigen gamma chain

1

0

High-throughput

0.513

High

155983

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

155985

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

156003

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

156019

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

156031

KSR2
Kinase suppressor of Ras 2

1

0

High-throughput

0.513

High

156033

TRM1L
TRMT1-like protein

1

0

High-throughput

0.513

High

156039

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

156041

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.513

High

156049

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

156060

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

0

High-throughput

0.513

High

156002

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

9

High-throughput

0.501

High

156052

PSKH2
Serine/threonine-protein kinase H2

1

1

High-throughput

0.489

High

155961

PFD6
Prefoldin subunit 6

1

3

High-throughput

0.479

High

155963

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

155966

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

155967

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.479

High

155970

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.479

High

155971

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

155974

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

155984

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

155986

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

155995

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

155998

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

156011

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

156016

RAE1L
mRNA export factor RAE1

1

1

High-throughput

0.479

High

156021

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

156022

BRD3
Bromodomain-containing protein 3

1

11

High-throughput

0.479

High

156024

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

156026

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

10

High-throughput

0.479

High

156029

Q6PK50
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

156030

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

156032

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

156036

NUDC3
NudC domain-containing protein 3

1

1

High-throughput

0.479

High

156040

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

156042

ASB13
Ankyrin repeat and SOCS box protein 13

1

3

High-throughput

0.479

High

156051

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

15

High-throughput

0.479

High

156053

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

156064

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

156067

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

156070

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

17

High-throughput

0.479

High

156071

PDRG1
p53 and DNA damage-regulated protein 1

1

2

High-throughput

0.479

High

156077

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

156078

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.470

High

155993

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

156034

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

156047

S7A6O
Probable RNA polymerase II nuclear localization protein SLC7A6OS

1

0

High-throughput

0.458

High

156059

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.458

High

156084

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

0

High-throughput

0.458

High

56562

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

155981

RPC22
Protein POLR1D, isoform 2

1

1

High-throughput

0.445

High

155979

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

156028

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

2

High-throughput

0.437

High

156046

Q96BE0
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.437

High

156056

Q9BPW0
Serine/threonine-protein phosphatase

1

10

High-throughput

0.437

High

156081

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

Small-scale

0.437

High

156025

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

156038

PALS1
Protein PALS1

1

0

High-throughput

0.426

High

155976

RET4
Retinol-binding protein 4

1

0

High-throughput

0.279

Low

156027

CHIC1
Cysteine-rich hydrophobic domain-containing protein 1

1

0

High-throughput

0.279

Low

118110

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

156045

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024