Protein: TNFB
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)

Gene: TNFB, LTA
Organism: Homo sapiens
Interactions: 30
UniProt ID: P01374

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0002876 - positive regulation of chronic inflammatory response to antigenic stimulus
GO:0002925 - positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352408

TNR1A
Tumor necrosis factor receptor superfamily member 1A

6

20

Small-scale

0.942

High

352413

TNFC
Lymphotoxin-beta

5

8

Small-scale

0.924

High

352409

TNR1B
Tumor necrosis factor receptor superfamily member 1B

3

20

Small-scale

0.858

High

352421

TNR14
Tumor necrosis factor receptor superfamily member 14

2

20

Small-scale

0.754

High

352424

ZNT2
Proton-coupled zinc antiporter SLC30A2

3

2

High-throughput

0.654

High

352402

TNFB
Lymphotoxin-alpha

1

8

Small-scale

0.647

High

352403

TNFA
Tumor necrosis factor

1

8

Small-scale

0.618

High

352410

TNR3
Tumor necrosis factor receptor superfamily member 3

1

20

Small-scale

0.618

High

352420

TBA1A
Tubulin alpha-1A chain

2

6

Small-scale

0.611

High

352404

LEG2
Galectin-2

1

1

Small-scale

0.589

High

352414

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.580

High

352407

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

352411

ACTB
Actin, cytoplasmic 1

1

7

High-throughput

0.536

High

216643

CREB3
Cyclic AMP-responsive element-binding protein 3

2

5

High-throughput

0.526

High

352406

UROM
Uromodulin

1

2

Small-scale

0.501

High

352405

TBB5
Tubulin beta chain

1

4

High-throughput

0.489

High

352417

TBB8
Tubulin beta-8 chain

1

4

High-throughput

0.489

High

352423

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.489

High

352427

DD19B
ATP-dependent RNA helicase DDX19B

1

4

High-throughput

0.489

High

56587

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

352415

BIRC2
Baculoviral IAP repeat-containing protein 2

1

6

Small-scale

0.445

High

352416

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

8

Small-scale

0.445

High

352412

TBA1B
Tubulin alpha-1B chain

1

6

Small-scale

0.437

High

352419

ANR40
Ankyrin repeat domain-containing protein 40

2

0

High-throughput

0.324

High

326966

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

352422

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

352418

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

352425

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low

352426

CLSPN
Claspin

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024