Protein: TOP2A
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)

Gene: TOP2A
Organism: Homo sapiens
Interactions: 451
UniProt ID: P11388

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000775 - chromosome, centromeric region
GO:0000793 - condensed chromosome
GO:0000819 - sister chromatid segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508952

TOP2B
DNA topoisomerase 2-beta

2

16

Small-scale

0.799

High

509006

TEBP
Prostaglandin E synthase 3

1

3

High-throughput

0.691

High

509038

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.691

High

509139

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.691

High

455031

PARP1
Poly [ADP-ribose] polymerase 1

4

2

Small-scale

0.687

High

509105

RBM4B
RNA-binding protein 4B

3

1

High-throughput

0.667

High

509172

ZN451
E3 SUMO-protein ligase ZNF451

3

1

Small-scale

0.667

High

385986

P53
Cellular tumor antigen p53

3

2

Small-scale

0.664

High

508801

XRCC5
X-ray repair cross-complementing protein 5

3

2

Small-scale

0.657

High

509014

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.656

High

243848

BRD4
Bromodomain-containing protein 4

3

12

High-throughput

0.656

High

345791

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.656

High

508917

H4
Histone H4

3

2

High-throughput

0.656

High

508998

CHD4
Chromodomain-helicase-DNA-binding protein 4

3

7

High-throughput

0.656

High

508936

RNF4
E3 ubiquitin-protein ligase RNF4

3

1

Small-scale

0.646

High

508935

H31
Histone H3.1

3

9

Small-scale

0.640

High

508848

BRCA1
Breast cancer type 1 susceptibility protein

2

3

Small-scale

0.634

High

508985

HDAC1
Histone deacetylase 1

2

3

Small-scale

0.631

High

224754

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.631

High

508932

UBC9
SUMO-conjugating enzyme UBC9

2

2

Small-scale

0.629

High

508934

CSK21
Casein kinase II subunit alpha

2

4

Small-scale

0.629

High

509056

PIAS4
E3 SUMO-protein ligase PIAS4

2

3

Small-scale

0.629

High

508830

3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

2

1

High-throughput

0.628

High

508831

RL10
Large ribosomal subunit protein uL16

2

1

High-throughput

0.628

High

509163

G3BP2
Ras GTPase-activating protein-binding protein 2

2

3

High-throughput

0.628

High

508839

CTNB1
Catenin beta-1

3

0

Small-scale

0.628

High

508800

XRCC6
X-ray repair cross-complementing protein 6

2

2

High-throughput

0.621

High

508886

BLM
RecQ-like DNA helicase BLM

1

1

Small-scale

0.618

High

508962

DHX9
ATP-dependent RNA helicase A

1

3

Small-scale

0.618

High

509111

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.618

High

508957

KPCD
Protein kinase C delta type

1

6

Small-scale

0.612

High

508304

TOP1
DNA topoisomerase 1

2

1

Small-scale

0.612

High

508938

PRKDC
DNA-dependent protein kinase catalytic subunit

2

2

Small-scale

0.612

High

322117

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

6

High-throughput

0.611

High

508838

MCM5
DNA replication licensing factor MCM5

2

1

High-throughput

0.611

High

508871

CTCF
Transcriptional repressor CTCF

2

1

Small-scale

0.611

High

508924

RL31
Large ribosomal subunit protein eL31

2

1

High-throughput

0.611

High

509103

H2B1L
Histone H2B type 1-L

2

10

High-throughput

0.611

High

509132

MET14
N6-adenosine-methyltransferase non-catalytic subunit

2

1

High-throughput

0.611

High

508875

TSP3
Thrombospondin-3

3

1

High-throughput

0.609

High

509076

CSN5
COP9 signalosome complex subunit 5

2

3

Small-scale

0.606

High

508885

PLK1
Serine/threonine-protein kinase PLK1

2

2

Small-scale

0.602

High

508902

SUMO2
Small ubiquitin-related modifier 2

2

4

High-throughput

0.602

High

508845

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.602

High

508899

RL15
Large ribosomal subunit protein eL15

2

0

High-throughput

0.602

High

509049

F131B
Protein FAM131B

2

0

High-throughput

0.602

High

509080

H2B1H
Histone H2B type 1-H

2

11

High-throughput

0.601

High

508978

ATM
Serine-protein kinase ATM

1

2

Small-scale

0.586

High

509099

CDC5L
Cell division cycle 5-like protein

2

0

Small-scale

0.585

High

401316

JUN
Transcription factor Jun

2

2

Small-scale

0.585

High

170230

TIF1A
Transcription intermediary factor 1-alpha

2

4

Small-scale

0.584

High

359603

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

4

High-throughput

0.584

High

508807

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

508832

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

2

High-throughput

0.584

High

508841

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.584

High

508945

H33
Histone H3.3

2

9

Small-scale

0.584

High

508976

TIF1B
Transcription intermediary factor 1-beta

2

4

Small-scale

0.584

High

509012

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.584

High

509023

SETMR
Histone-lysine N-methyltransferase SETMAR

2

1

Small-scale

0.584

High

509081

FBXW7
F-box/WD repeat-containing protein 7

2

5

Small-scale

0.584

High

509138

ANLN
Anillin

2

1

High-throughput

0.584

High

509152

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.584

High

509131

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

4

Small-scale

0.578

High

508795

TOP2A
DNA topoisomerase 2-alpha

1

16

Small-scale

0.575

High

509177

ASB3
Ankyrin repeat and SOCS box protein 3

2

2

High-throughput

0.574

High

508997

PSF1
DNA replication complex GINS protein PSF1

1

1

Small-scale

0.561

High

509053

RN168
E3 ubiquitin-protein ligase RNF168

1

1

Small-scale

0.561

High

509098

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

8

Small-scale

0.561

High

509118

CCDC8
Coiled-coil domain-containing protein 8

2

0

High-throughput

0.559

High

169235

MDM4
Protein Mdm4

1

0

Small-scale

0.537

High

509121

CDT1
DNA replication factor Cdt1

1

0

Small-scale

0.537

High

508834

MK01
Mitogen-activated protein kinase 1

1

2

Small-scale

0.536

High

133297

NOP56
Nucleolar protein 56

1

2

High-throughput

0.536

High

146148

ARI1A
AT-rich interactive domain-containing protein 1A

1

4

Small-scale

0.536

High

176930

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

4

High-throughput

0.536

High

217428

AIRE
Autoimmune regulator

1

10

Small-scale

0.536

High

260736

H2AY
Core histone macro-H2A.1

1

9

High-throughput

0.536

High

295923

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.536

High

324729

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.536

High

364823

FRIL
Ferritin light chain

1

3

High-throughput

0.536

High

368882

ESR1
Estrogen receptor

1

7

High-throughput

0.536

High

417887

NPM
Nucleophosmin

1

2

High-throughput

0.536

High

449510

HMGB1
High mobility group protein B1

1

4

High-throughput

0.536

High

469933

H2AZ
Histone H2A.Z

1

9

High-throughput

0.536

High

508805

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.536

High

508809

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.536

High

508810

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

508821

VDAC1
Voltage-dependent anion-selective channel protein 1

1

1

High-throughput

0.536

High

508824

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.536

High

508825

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.536

High

508828

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.536

High

508835

LTK
Leukocyte tyrosine kinase receptor

1

1

High-throughput

0.536

High

508842

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.536

High

508844

TCF7
Transcription factor 7

1

2

High-throughput

0.536

High

508846

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.536

High

508854

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

508857

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.536

High

508858

PRS6B
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.536

High

508874

PSB3
Proteasome subunit beta type-3

1

3

High-throughput

0.536

High

508879

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.536

High

508881

FXR2
RNA-binding protein FXR2

1

3

High-throughput

0.536

High

508889

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

3

High-throughput

0.536

High

508893

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.536

High

508894

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

High-throughput

0.536

High

508895

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.536

High

508896

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.536

High

508897

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.536

High

508901

RL27
Large ribosomal subunit protein eL27

1

1

High-throughput

0.536

High

508904

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.536

High

508905

PRS8
26S proteasome regulatory subunit 8

1

3

High-throughput

0.536

High

508907

RS15A
Small ribosomal subunit protein uS8

1

1

High-throughput

0.536

High

508908

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

508912

RS18
Small ribosomal subunit protein uS13

1

1

High-throughput

0.536

High

508914

PRS10
26S proteasome regulatory subunit 10B

1

3

High-throughput

0.536

High

508920

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.536

High

508925

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.536

High

508926

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.536

High

508927

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

508931

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.536

High

508933

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

508937

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.536

High

508941

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

1

High-throughput

0.536

High

508946

CDKL1
Cyclin-dependent kinase-like 1

1

2

High-throughput

0.536

High

508948

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

508955

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.536

High

508959

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.536

High

508963

SSRP1
FACT complex subunit SSRP1

1

7

High-throughput

0.536

High

508965

RBBP4
Histone-binding protein RBBP4

1

4

High-throughput

0.536

High

508971

ILF3
Interleukin enhancer-binding factor 3

1

7

High-throughput

0.536

High

508977

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.536

High

508979

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.536

High

508984

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

1

High-throughput

0.536

High

508987

KGP1
cGMP-dependent protein kinase 1

1

6

High-throughput

0.536

High

508993

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.536

High

508995

CAPR1
Caprin-1

1

3

High-throughput

0.536

High

508999

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.536

High

509001

CND2
Condensin complex subunit 2

1

2

High-throughput

0.536

High

509017

H2A2C
Histone H2A type 2-C

1

7

High-throughput

0.536

High

509018

H2B2E
Histone H2B type 2-E

1

11

High-throughput

0.536

High

509019

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.536

High

509024

DJC21
DnaJ homolog subfamily C member 21

1

1

High-throughput

0.536

High

509030

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.536

High

509037

COX15
Heme A synthase COX15

1

1

High-throughput

0.536

High

509042

YTHD3
YTH domain-containing family protein 3

1

1

High-throughput

0.536

High

509044

PB1
Protein polybromo-1

1

14

High-throughput

0.536

High

509046

KTN1
Kinectin

1

2

High-throughput

0.536

High

509050

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.536

High

509051

H2A2B
Histone H2A type 2-B

1

6

High-throughput

0.536

High

509065

NEK9
Serine/threonine-protein kinase Nek9

1

1

High-throughput

0.536

High

509067

GRK7
Rhodopsin kinase GRK7

1

5

High-throughput

0.536

High

509070

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.536

High

509073

TFG
Protein TFG

1

2

High-throughput

0.536

High

509078

CUL5
Cullin-5

1

4

High-throughput

0.536

High

509079

H2A1C
Histone H2A type 1-C

1

7

High-throughput

0.536

High

509084

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

509093

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

2

High-throughput

0.536

High

509096

SRPK1
SRSF protein kinase 1

1

5

High-throughput

0.536

High

509097

IWS1
Protein IWS1 homolog

1

1

High-throughput

0.536

High

509100

RING2
E3 ubiquitin-protein ligase RING2

1

5

High-throughput

0.536

High

509102

H2A1J
Histone H2A type 1-J

1

7

High-throughput

0.536

High

509116

LSG1
Large subunit GTPase 1 homolog

1

1

High-throughput

0.536

High

509120

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

509122

FOXP1
Forkhead box protein P1

1

3

High-throughput

0.536

High

509126

PLK3
Serine/threonine-protein kinase PLK3

1

1

High-throughput

0.536

High

509136

DCP1A
mRNA-decapping enzyme 1A

1

1

High-throughput

0.536

High

509147

H2AW
Core histone macro-H2A.2

1

9

High-throughput

0.536

High

509151

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

509155

BAZ1B
Tyrosine-protein kinase BAZ1B

1

13

High-throughput

0.536

High

509156

FOXD3
Forkhead box protein D3

1

3

High-throughput

0.536

High

509157

KS6A6
Ribosomal protein S6 kinase alpha-6

1

1

High-throughput

0.536

High

509165

SRPK3
SRSF protein kinase 3

1

5

High-throughput

0.536

High

509167

DRG1
Developmentally-regulated GTP-binding protein 1

1

2

High-throughput

0.536

High

509169

KLH20
Kelch-like protein 20

1

2

High-throughput

0.536

High

509176

PRC2C
Protein PRRC2C

1

3

High-throughput

0.536

High

314211

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.517

High

508882

SMCA4
Transcription activator BRG1

1

11

Small-scale

0.515

High

508884

HMGA2
High mobility group protein HMGI-C

1

2

Small-scale

0.515

High

509016

H31T
Histone H3.1t

1

9

High-throughput

0.515

High

181496

CLOCK
Circadian locomoter output cycles protein kaput

1

0

High-throughput

0.513

High

255028

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

268383

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.513

High

283371

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.513

High

335039

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.513

High

400216

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

400438

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.513

High

444057

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.513

High

508796

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

508797

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.513

High

508803

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

508813

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

508815

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

508816

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

508818

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.513

High

508837

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.513

High

508850

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.513

High

508851

FEN1
Flap endonuclease 1

1

0

High-throughput

0.513

High

508861

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

508862

RL21
Large ribosomal subunit protein eL21

1

0

High-throughput

0.513

High

508863

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

508864

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

508865

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.513

High

508866

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

508880

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

508898

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.513

High

508900

MGN
Protein mago nashi homolog

1

0

High-throughput

0.513

High

508903

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.513

High

508906

RS8
Small ribosomal subunit protein eS8

1

0

High-throughput

0.513

High

508911

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.513

High

508913

RS29
Small ribosomal subunit protein uS14

1

0

High-throughput

0.513

High

508915

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.513

High

508919

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

508921

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

508923

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

508930

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.513

High

508942

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.513

High

508944

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

508960

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

508973

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

0

High-throughput

0.513

High

508988

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.513

High

508990

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

508991

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.513

High

509026

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.513

High

509031

ULK3
Serine/threonine-protein kinase ULK3

1

0

High-throughput

0.513

High

509033

GGYF2
GRB10-interacting GYF protein 2

1

0

High-throughput

0.513

High

509035

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

509036

RS27L
Ribosomal protein eS27-like

1

0

High-throughput

0.513

High

509045

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

509060

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

509072

TRIB2
Tribbles homolog 2

1

0

High-throughput

0.513

High

509107

CG050
Uncharacterized protein C7orf50

1

0

High-throughput

0.513

High

509108

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

509109

CENPK
Centromere protein K

1

0

High-throughput

0.513

High

509110

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.513

High

509137

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.513

High

509153

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.513

High

509159

INTU
Protein inturned

1

0

High-throughput

0.513

High

509166

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

509171

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

509175

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

283093

DFFB
DNA fragmentation factor subunit beta

1

1

Small-scale

0.501

High

397129

KPCG
Protein kinase C gamma type

1

6

Small-scale

0.501

High

408541

KPCB
Protein kinase C beta type

1

6

Small-scale

0.501

High

508811

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.501

High

508989

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

Small-scale

0.501

High

509077

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.501

High

509158

AGO2
Protein argonaute-2

1

1

Small-scale

0.500

High

508983

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.493

High

509134

RESF1
Retroelement silencing factor 1

1

0

High-throughput

0.493

High

508799

CADH1
Cadherin-1

1

1

High-throughput

0.489

High

508867

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.489

High

508953

LMNB2
Lamin-B2

1

4

High-throughput

0.489

High

509041

UBE3B
Ubiquitin-protein ligase E3B

1

5

High-throughput

0.489

High

509061

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.489

High

508855

WASP
Actin nucleation-promoting factor WAS

1

2

Small-scale

0.484

High

162370

XPO1
Exportin-1

1

0

Small-scale

0.479

High

119120

LEG9
Galectin-9

1

1

High-throughput

0.479

High

122465

MEN1
Menin

1

1

High-throughput

0.479

High

125118

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

130715

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

3

Small-scale

0.479

High

148333

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

179530

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

209621

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

226365

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

233175

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

233809

HBP1
HMG box-containing protein 1

1

2

High-throughput

0.479

High

241433

H2B1K
Histone H2B type 1-K

1

11

High-throughput

0.479

High

255465

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

266903

SRS10
Serine/arginine-rich splicing factor 10

1

2

Small-scale

0.479

High

267866

EED
Polycomb protein EED

1

7

High-throughput

0.479

High

282811

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

7

High-throughput

0.479

High

308360

KI20A
Kinesin-like protein KIF20A

1

5

High-throughput

0.479

High

331709

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

Small-scale

0.479

High

391523

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

397743

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.479

High

420797

H2B1J
Histone H2B type 1-J

1

11

High-throughput

0.479

High

441850

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

508812

KCRS
Creatine kinase S-type, mitochondrial

1

1

High-throughput

0.479

High

508814

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

508822

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.479

High

508823

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

7

Small-scale

0.479

High

508826

BRD2
Bromodomain-containing protein 2

1

14

High-throughput

0.479

High

508829

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.479

High

508833

PSB5
Proteasome subunit beta type-5

1

2

Small-scale

0.479

High

508836

PML
Protein PML

1

4

High-throughput

0.479

High

508840

BMI1
Polycomb complex protein BMI-1

1

2

Small-scale

0.479

High

508849

COIL
Coilin

1

1

High-throughput

0.479

High

508853

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

508856

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

7

High-throughput

0.479

High

508859

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

508869

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

508870

CENPA
Histone H3-like centromeric protein A

1

9

High-throughput

0.479

High

508873

CEBPD
CCAAT/enhancer-binding protein delta

1

6

Small-scale

0.479

High

508876

RBP2
E3 SUMO-protein ligase RanBP2

1

2

Small-scale

0.479

High

508877

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

508887

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

6

High-throughput

0.479

High

508888

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

508890

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

508891

H2B1D
Histone H2B type 1-D

1

11

High-throughput

0.479

High

508910

1433E
14-3-3 protein epsilon

1

2

Small-scale

0.479

High

508916

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

508918

H2B1C
Histone H2B type 1-C/E/F/G/I

1

11

High-throughput

0.479

High

508928

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.479

High

508929

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

Small-scale

0.479

High

508939

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

508940

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

508943

RL36A
Large ribosomal subunit protein eL42

1

1

High-throughput

0.479

High

508950

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

508951

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

508954

ERCC6
DNA excision repair protein ERCC-6

1

13

Small-scale

0.479

High

508956

TLE2
Transducin-like enhancer protein 2

1

6

High-throughput

0.479

High

508958

RING1
E3 ubiquitin-protein ligase RING1

1

5

Small-scale

0.479

High

508961

FOXM1
Forkhead box protein M1

1

3

Small-scale

0.479

High

508967

EP300
Histone acetyltransferase p300

1

12

High-throughput

0.479

High

508970

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

7

High-throughput

0.479

High

508972

RFA4
Replication protein A 30 kDa subunit

1

2

High-throughput

0.479

High

508974

CBX3
Chromobox protein homolog 3

1

2

High-throughput

0.479

High

508975

ERCC8
DNA excision repair protein ERCC-8

1

8

High-throughput

0.479

High

508981

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

508982

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

508986

CUL2
Cullin-2

1

4

Small-scale

0.479

High

508992

RCN2
Reticulocalbin-2

1

2

High-throughput

0.479

High

508996

RBM39
RNA-binding protein 39

1

2

High-throughput

0.479

High

509000

CUL7
Cullin-7

1

1

High-throughput

0.479

High

509002

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

509003

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

509004

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

509005

BRD3
Bromodomain-containing protein 3

1

16

High-throughput

0.479

High

509007

RBBP5
Retinoblastoma-binding protein 5

1

7

High-throughput

0.479

High

509008

ZMY11
Zinc finger MYND domain-containing protein 11

1

6

Small-scale

0.479

High

509009

PCBP1
Poly(rC)-binding protein 1

1

1

Small-scale

0.479

High

509015

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

509021

MIDN
Midnolin

1

1

High-throughput

0.479

High

509022

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

509029

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

509032

WDR82
WD repeat-containing protein 82

1

11

High-throughput

0.479

High

509034

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

509047

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

509048

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

509052

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

509054

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

4

Small-scale

0.479

High

509055

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.479

High

509057

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.479

High

509058

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

509064

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

509066

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

509068

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

509071

DDB2
DNA damage-binding protein 2

1

10

High-throughput

0.479

High

509074

HDAC2
Histone deacetylase 2

1

4

Small-scale

0.479

High

509075

KAT6A
Histone acetyltransferase KAT6A

1

8

High-throughput

0.479

High

509086

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

509087

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.479

High

509088

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

509089

MBD6
Methyl-CpG-binding domain protein 6

1

3

High-throughput

0.479

High

509101

NECD
Necdin

1

1

High-throughput

0.479

High

509104

VRK1
Serine/threonine-protein kinase VRK1

1

2

High-throughput

0.479

High

509106

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

5

High-throughput

0.479

High

509112

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

509114

WWTR1
WW domain-containing transcription regulator protein 1

1

6

High-throughput

0.479

High

509115

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

High-throughput

0.479

High

509123

P63
Tumor protein 63

1

2

Small-scale

0.479

High

509125

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

509127

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

12

High-throughput

0.479

High

509128

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

509130

ECT2
Protein ECT2

1

4

High-throughput

0.479

High

509133

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

4

High-throughput

0.479

High

509140

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

Small-scale

0.479

High

509141

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

509143

NLE1
Notchless protein homolog 1

1

4

High-throughput

0.479

High

509148

MBD5
Methyl-CpG-binding domain protein 5

1

1

High-throughput

0.479

High

509149

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

509150

PAK5
Serine/threonine-protein kinase PAK 5

1

1

Small-scale

0.479

High

509154

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

2

High-throughput

0.479

High

509162

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.479

High

509170

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

509173

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

Small-scale

0.479

High

509174

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

63967

DUXA
Double homeobox protein A

1

0

High-throughput

0.458

High

161778

ZN263
Zinc finger protein 263

1

0

Small-scale

0.458

High

414141

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

450691

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

503324

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

508802

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.458

High

508819

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

508843

VGFR2
Vascular endothelial growth factor receptor 2

1

0

High-throughput

0.458

High

508847

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

508852

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

508860

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

508868

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

508878

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

508909

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

508947

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

508968

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

508969

MERTK
Tyrosine-protein kinase Mer

1

0

High-throughput

0.458

High

509010

ELOC
Elongin-C

1

0

Small-scale

0.458

High

509011

TERF2
Telomeric repeat-binding factor 2

1

0

Small-scale

0.458

High

509013

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

509040

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

509043

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

509059

ZBT38
Zinc finger and BTB domain-containing protein 38

1

0

Small-scale

0.458

High

509082

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

509085

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

509091

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

509092

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

509095

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

509135

SHCAF
SIN3-HDAC complex-associated factor

1

0

Small-scale

0.458

High

509144

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

509145

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

56593

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

101621

F8VR69
Ribosomal protein L6

1

1

High-throughput

0.445

High

110708

H3BUK8
Large ribosomal subunit protein eL13

1

1

High-throughput

0.445

High

112139

M0R1M6
Ubiquitin-ribosomal protein eL40 fusion protein

1

3

High-throughput

0.445

High

508798

KCRU
Creatine kinase U-type, mitochondrial

1

1

High-throughput

0.445

High

508806

ITF2
Transcription factor 4

1

1

Small-scale

0.445

High

508808

H2AX
Histone H2AX

1

8

Small-scale

0.445

High

508883

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.445

High

508922

RS30
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein

1

2

High-throughput

0.445

High

508980

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

509083

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.445

High

509146

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

509161

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.445

High

362748

FINC
Fibronectin

1

1

High-throughput

0.437

High

509028

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.437

High

509113

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

509119

CAD19
Cadherin-19

1

2

High-throughput

0.437

High

509124

MTRFR
Mitochondrial translation release factor in rescue

1

1

High-throughput

0.437

High

509160

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

High-throughput

0.437

High

508827

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.426

High

508949

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

508966

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

509027

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.426

High

508872

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

509094

Q96KY9
CDH19 protein

1

2

High-throughput

0.407

High

508817

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.298

High

509142

FBX28
F-box only protein 28

1

0

Small-scale

0.292

High

508820

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

508892

SC61G
Protein transport protein Sec61 subunit gamma

1

0

High-throughput

0.279

Low

508964

VAC14
Protein VAC14 homolog

1

0

High-throughput

0.279

Low

509025

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

509039

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

0

High-throughput

0.279

Low

509063

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.279

Low

509090

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

509129

RDD1
Required for drug-induced death protein 1

1

0

High-throughput

0.279

Low

509164

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.279

Low

509062

FXL13
F-box and leucine-rich repeat protein 13

1

0

High-throughput

0.269

Low

509117

MAGT1
Magnesium transporter protein 1

1

0

High-throughput

0.269

Low

508804

ITA4
Integrin alpha-4

1

0

High-throughput

0.249

Low

508994

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

509020

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low

509069

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.249

Low

509168

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024